Current Status of Auricular Reconstruction Strategy Development
Current Status of Auricular Reconstruction Strategy Development
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DOI：
10.1097/scs.0000000000009908
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发表时间：
2024-05-01
影响因子：
0.9
通讯作者：
Liao，Junlin
中科院分区：
文献类型：
--
作者：
Wei，Yi;Li，Li;Liao，Junlin
小耳畸形对患者有严重的生理和心理影响，耳廓再造术可以改善美学和功能，减轻心理问题。小耳畸形是一种由环境和遗传因素共同作用引起的先天性疾病，临床表现复杂。分类评估有助于确定治疗策略。耳廓再造是重度小耳畸形的主要治疗方法，其重点在于耳廓支架材料的选择、耳廓形态的构建以及皮肤和软组织支架的覆盖。自体肋软骨和人工合成材料都是耳廓再造的支架材料，各有优缺点。已经开发了用于实现皮肤和软组织支架覆盖的方法以包括非扩张和扩张技术。近年来，有限元分析等数字化辅助技术的应用有助于优化手术效果，减少并发症。组织工程软骨支架和三维生物打印技术在耳再造领域发展迅速。本文就小耳畸形的发病率、分类、耳廓支架材料的选择、手术方法的演变以及数字化辅助技术在耳再造中的应用现状进行了探讨，旨在为临床医师提供个性化耳再造手术的参考。本文的重点是组织工程和三维生物打印技术在耳再造领域的应用现状和面临的挑战，以及未来的展望。
Microtia has severe physical and psychological impacts on patients, and auricular reconstruction offers improved esthetics and function, alleviating psychological issues. Microtia is a congenital disease caused by a multifactorial interaction of environmental and genetic factors, with complex clinical manifestations. Classification assessment aids in determining treatment strategies. Auricular reconstruction is the primary treatment for severe microtia, focusing on the selection of auricular scaffold materials, the construction of auricular morphology, and skin and soft tissue scaffold coverage. Autologous rib cartilage and synthetic materials are both used as scaffold materials for auricular reconstruction, each with advantages and disadvantages. Methods for achieving skin and soft tissue scaffold coverage have been developed to include nonexpansion and expansion techniques. In recent years, the application of digital auxiliary technology such as finite element analysis has helped optimize surgical outcomes and reduce complications. Tissue-engineered cartilage scaffolds and 3-dimensional bioprinting technology have rapidly advanced in the field of ear reconstruction. This article discusses the prevalence and classification of microtia, the selection of auricular scaffolds, the evolution of surgical methods, and the current applications of digital auxiliary technology in ear reconstruction, with the aim of providing clinical physicians with a reference for individualized ear reconstruction surgery. The focus of this work is on the current applications and challenges of tissue engineering and 3-dimensional bioprinting technology in the field of ear reconstruction, as well as future prospects.