Enantioselective synthesis of benzofurans and benzoxazines via an olefin cross-metathesis-intramolecular oxo-Michael reaction.
Enantioselective synthesis of benzofurans and benzoxazines via an olefin cross-metathesis-intramolecular oxo-Michael reaction.
复制标题
DOI：
10.1039/c3cc43937b
复制
发表时间：
2013-08
影响因子：
4.9
通讯作者：
Junwei Zhang;Quan Cai;Q. Gu;Xiao-Xin Shi;S. You
中科院分区：
文献类型：
--
作者：
Junwei Zhang;Quan Cai;Q. Gu;Xiao-Xin Shi;S. You
发现手性磷酸和Hoveyda-Grubbs II催化邻烯丙基苯酚和烯酮的烯烃交叉复分解-分子内氧代-Michael级联反应，以中等至良好的产率和对映选择性提供各种苯并呋喃和苯并恶嗪衍生物。
Chiral phosphoric acid and Hoveyda-Grubbs II were found to catalyze an olefin cross-metathesis-intramolecular oxo-Michael cascade reaction of the ortho-allylphenols and enones to provide a variety of benzofuran and benzoxazine derivatives in moderate to good yields and enantioselectivity.