Relationship between socioeconomic status and prostate cancer (incidence, aggressiveness, treatment with curative intent, and mortality): a spatial analysis using population-based cancer registry data.
Relationship between socioeconomic status and prostate cancer (incidence, aggressiveness, treatment with curative intent, and mortality): a spatial analysis using population-based cancer registry data.
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DOI：
10.1016/j.respe.2021.07.007
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发表时间：
2021-11-26
影响因子：
0.9
通讯作者：
Ganry, O.
中科院分区：
文献类型：
--
作者：
Ben Khadhra, H.;Saint, F.;Ganry, O.
背景- 在特定地理区域，与前列腺癌相关的发病率和死亡率可能与社会经济贫困程度有关。索姆河地区（法国北方的一个地区）被认为是经济上处于不利地位的地区，存在重大的地域差异。本研究的目的是评估社会经济水平对前列腺癌的影响，使用基于人群的癌症登记数据。方法. - 2006年至2010年期间前列腺癌病例的数据来源是索姆癌症登记处（法国亚眠）。社会经济状况是根据欧洲贫困指数衡量的，该指数用于根据社会贫困程度对每个“IRIS”地理单位（法国人口普查数据所涉的最小城市以下地理实体）进行分类。对于空间分析，我们考虑了分层广义线性模型。结果- 在空间分析中，前列腺癌的发病率较高，在条件较差的地区和治疗的频率与治疗的意图是在最不利的地区较低。最贫困地区的癌症侵袭性和死亡率较高：相对危险度（RR）= 1.36; 95%CI：[1.09; 1.73]和RR=3.09 [1.70; 5.59]。结论- 我们的研究结果证明了社会经济剥夺与前列腺癌之间的显着关联，社会经济地位最低的男性预后更差。(c)2021 Elsevier Masson SAS。All rights reserved.
Background. - Morbidity and mortality associated with prostate cancer in a given geographic area might be related to the level of socioeconomic deprivation. The Somme area (a region of northern France) is considered economically disadvantaged, with major territorial disparities. The aim of this study was to assess the impact of the socioeconomic level on prostate cancer, using data from a population-based cancer registry. Methods. - The source of data on cases of prostate cancer between 2006 and 2010 was the Somme cancer registry (Amiens, France). Socioeconomic status was measured according to the European Deprivation Index (EDI), which was used to classify each geographical "IRIS" unit (the smallest sub-municipal geographical entity for which French census data are available) according to its level of social deprivation. For spatial analysis, we considered a hierarchical generalized linear model. Results. - In the spatial analysis, prostate cancer incidence was higher in the less disadvantaged areas and treatment frequency with curative intent was lower in the most disadvantaged areas. Cancer aggressiveness and mortality were higher in the most disadvantaged areas: relative risk (RR) = 1.36; 95% CI: [1.09; 1.73] and RR=3.09 [1.70; 5.59], respectively. Conclusion. - Our results evidenced a significant association between socioeconomic deprivation and prostate cancer, with worse outcomes among men with the lowest socioeconomic status. (c) 2021 Elsevier Masson SAS. All rights reserved.