Copper-Catalyzed Twofold Silylmetalation of Alkynes
Copper-Catalyzed Twofold Silylmetalation of Alkynes
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DOI：
10.1055/s-0037-1611869
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发表时间：
2019-06
期刊：
影响因子：
2
通讯作者：
Hiroki Yamagishi;Jun Shimokawa;H. Yorimitsu
中科院分区：
文献类型：
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作者：
Hiroki Yamagishi;Jun Shimokawa;H. Yorimitsu
摘要 首次实现了跨 C=C 三键的双重甲硅烷基金属化。在催化量的氰化铜存在下，用由乙硅烷和t-BuOK原位产生的甲硅烷基钾物质处理，二芳基乙炔转化为1,2-二金属化的1,2-二甲硅烷基-1,2-二芳基乙烷。随后，二金属化物质被质子化，产生一系列 1,2-二甲硅烷基-1,2-二芳基乙烷。
Abstract The first twofold silylmetalation across a C≡C triple bond was achieved. In the presence of a catalytic amount of copper cyanide, diarylacetylenes were converted into 1,2-dimetalated 1,2-disilyl-1,2-diarylethanes on treatment with silylpotassium species generated in situ from disilane and t-BuOK. The dimetalated species were subsequently protonated to yield a series of 1,2-disilyl-1,2-diarylethanes.