False memory in schizophrenia patients with and without delusions

False memory in schizophrenia patients with and without delusions
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DOI:
10.1016/j.psychres.2009.02.006
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发表时间:
2010-07-30
影响因子:
11.3
通讯作者:
McKenna, Peter J.
McKenna, Peter J.
中科院分区:
医学2区
文献类型:
--
作者:
Bhatt, Reena;Laws, Keith R.;McKenna, Peter J.

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妄想是固定的“错误信念”,虽然是精神分裂症的标志性特征,但以前没有研究过妄想是否与“错误记忆”有关。我们使用经典的Deese-Roediger-McDermott(DRM)范式比较了目前正在经历妄想(艾德)的精神分裂症患者、未经历妄想(ND)的患者和健康对照参与者的错误记忆产生。艾德组回忆起两倍的假阳性记忆(即,记忆以前没有见过的单词)作为对照组和关键的ND组。两组患者也比健康对照组识别出更少的正确单词,并且都对他们的错误记忆表现出更大的信心;然而,在识别任务中,艾德组比ND组做出更多的假阴性(即拒绝以前看到的单词)高信心反应。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
Delusions are fixed 'false beliefs' and, although a hallmark feature of schizophrenia, no previous study has examined if delusions might be related to 'false memories'. We used the classic Deese-Roediger-McDermott (DRM) paradigm to compare false memory production in schizophrenia patients who were currently experiencing delusions (ED), patients not experiencing delusions (ND) and healthy control participants. The ED group recalled twice as many false-positive memories (i.e., memory for words not previously seen) as both the controls and crucially, the ND group. Both patient groups also recognised fewer correct words than the healthy controls and both showed greater confidence in their false memories; however, on the recognition task, the ED group made more false-negative (i.e. rejecting previously seen words) high confidence responses than the ND group. (C) 2009 Elsevier Ireland Ltd. All rights reserved.