Analysis of bone mass and its relationship with body composition in school-aged children and adolescents based on stage of puberty and site specificity A retrospective case-control study
Analysis of bone mass and its relationship with body composition in school-aged children and adolescents based on stage of puberty and site specificity A retrospective case-control study
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DOI：
10.1097/md.0000000000014005
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发表时间：
2019-02-01
期刊：
影响因子：
1.6
通讯作者：
Xiong, Feng
中科院分区：
文献类型：
--
作者：
Song, Cui;Zhu, Min;Xiong, Feng
本研究的目的是更好地了解基于青春期不同阶段的骨量与身体成分的关系，并阐明与骨量相比，中国重庆学龄儿童和青少年的特定部位脂肪量和瘦体重（FM和LM）的贡献。共招募了1179名男性和女性健康受试者。采用双能X线骨密度仪（DXA）测量骨矿含量（BMC）、骨密度（BMD）、骨面积、FM和LM。脂肪质量和瘦体重指数（分别为FMI和LMI）分别计算为FM（kg）和LM（kg）除以身高（米）的平方。青春期后男孩的大多数骨量指标均显著高于同一阶段的女孩（P < .001）。无论性别和青春期阶段如何，骨量正常的受试者比例增加，而骨量减少和骨质疏松的受试者比例随着体重增加而减少（P <0.01）。FM和LM与骨量显著正相关，无论性别和青春期阶段（P < .0001）。FMI和LMI在大多数情况下与骨量显著正相关（P <0.0001）。FM和LM的四个分量与TB和TBHL的BMD和BMC呈线性显著相关。其中，头脂肪质量和头瘦肉质量表现出最大的统计贡献。在评估骨骼状态的过程中，我们建议测量脂肪和瘦肉质量，包括头部的脂肪和瘦肉质量。
The aim of this study was to better understand the relationship of bone mass with body composition based on different stages of puberty and to illuminate the contribution of site-specific fat mass and lean mass (FM and LM) compared with bone mass in school-aged children and adolescents in Chongqing, China. A total of 1179 healthy subjects of both sexes were recruited. Bone mineral content (BMC), bone mineral density (BMD), bone area, and both FM and LM were measured by dual-energy X-ray absorptiometry (DXA). The fat mass and lean mass indexes (FMI and LMI, respectively) were calculated as the FM (kg) and LM (kg) divided by the height in meters squared, respectively. Most of the bone mass indicators were significantly higher for postpubertal boys than for girls at the same stage (P < .001). The proportion of subjects with normal bone mass increased, while the proportion of subjects with osteopenia and osteoporosis decreased with increased body weight regardless of gender and puberty stage (P < .01). FM and LM were significantly positively related to bone mass regardless of gender and puberty stage (P < .0001). FMI and LMI were significantly positively related to bone mass in most conditions (P P < .0001, respectively). Four components of the FM and LM were linearly and significantly associated with BMD and BMC for TB and TBHL. Among them, the head fat mass and head lean mass showed the greatest statistical contribution. In the process of assessing bone status, we recommend measuring fat and lean masses, including the fat and lean masses of the head.