Sequence analysis Blast 2 GO : a universal tool for annotation , visualization and analysis in functional genomics research

Sequence analysis Blast 2 GO : a universal tool for annotation , visualization and analysis in functional genomics research
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发表时间:
2005
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通讯作者:
Ana Conesa;Stefan Götz;Juan Miguel García-Gómez;Javier Terol;Manuel Talón;Montserrat Robles
Ana Conesa;Stefan Götz;Juan Miguel García-Gómez;Javier Terol;Manuel Talón;Montserrat Robles
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作者:
Ana Conesa;Stefan Götz;Juan Miguel García-Gómez;Javier Terol;Manuel Talón;Montserrat Robles

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摘要:我们在这里介绍Blast2GO(B2G),这是一个研究工具,设计的主要目的是实现基于基因本体论(GO)的数据挖掘,对尚未提供GO注释的序列数据进行挖掘。一个应用程序中的B2G关节围棋注释基于统计分析的相似性搜索,并在有向无环图上突出显示。这一工具为非模式物种的功能基因组研究提供了一个合适的平台。B2G是一个直观和交互的桌面应用程序,允许监控和理解整个注释和分析过程。可获得性:Blast2GO可通过Java Web Start免费获得,网址为http://www.blast2go.de。补充材料:http://www.blast2go.de->评估联系人:acones a@ivia.es;stefang@fa.upv.es
Summary: We present here Blast2GO (B2G), a research tool designed with the main purpose of enabling Gene Ontology (GO) based data mining on sequence data for which no GO annotation is yet available. B2G joints in one application GO annotation based on similarity searches with statistical analysis and highlighted visualization on directed acyclic graphs. This tool offers a suitable platform for functional genomics research in non-model species. B2G is an intuitive and interactive desktop application that allows monitoring and comprehension of the whole annotation and analysis process. Availability: Blast2GO is freely available via Java Web Start at http://www.blast2go.de Supplementary material: http://www.blast2go.de -> Evaluation Contact: aconesa@ivia.es; stefang@fis.upv.es