Myxoid liposarcoma: Appearance at MR imaging with histologic correlation

Myxoid liposarcoma: Appearance at MR imaging with histologic correlation
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DOI:
10.1148/radiographics.20.4.g00jl021007
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发表时间:
2000-07-01
期刊:
影响因子:
5.5
通讯作者:
Lee, HG
Lee, HG
中科院分区:
医学1区
文献类型:
--
作者:
Sung, MS;Kang, HS;Lee, HG

文献摘要

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虽然黏液样脂肪肉瘤是脂肪肉瘤的一个亚型,但由于缺乏脂肪信号强度,磁共振成像可能很难建立正确的诊断。如果不使用钆造影剂,肿瘤甚至可能与囊性肿瘤相似。粘液样脂肪肉瘤的MR成像异常范围很广,取决于脂肪和粘液样物质的量,细胞和血管的程度,以及坏死的存在。大多数粘液样脂肪肉瘤有花边状或线状、无定形的脂肪灶。有些粘液样脂肪肉瘤在平扫时呈囊性,但在增强扫描时却像其他实性肿块一样增强。肿瘤内的强化区表现为细胞结构和血管增多;非强化区表现为坏死、细胞结构减少和粘液物质积聚。钆增强成像在粘液样脂肪肉瘤与良性囊性肿瘤的鉴别诊断中具有重要意义。MRI对粘液样脂肪肉瘤的定性诊断在粘液样脂肪肉瘤的治疗中起着重要作用。
Although myxoid liposarcoma is a subtype of liposarcoma, it may be difficult to establish the correct diagnosis with magnetic resonance (MR) imaging due to the lack of fat signal intensity. Without the administration of gadolinium contrast material, the tumor may even mimic a cystic tumor. A spectrum of MR imaging abnormalities occur in myxoid liposarcoma, depending on the amount of fat and myxoid material, the degree of cellularity and vascularity, and the presence of necrosis. Most myxoid liposarcomas have lacy or linear, amorphous foci of fat. Some myxoid liposarcomas appear to be cystic at nonenhanced MR imaging, although they enhance like other solid masses at contrast material-enhanced MR imaging. The enhancing areas within the tumor represent increased cellularity and vascularity; the nonenhancing areas represent necrosis, reduced cellularity, and accumulated mucinous material. Gadolinium-enhanced imaging is important in differentiating myxoid liposarcoma from benign cystic tumors. Characterization of the tumor with MR imaging plays an important role in the management of myxoid liposarcoma.