Residual effects of eszopiclone on daytime alertness, psychomotor, physical performance and subjective evaluations
Residual effects of eszopiclone on daytime alertness, psychomotor, physical performance and subjective evaluations
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艾司佐匹克隆对日间警觉性、精神运动、身体表现和主观评价的残留影响
DOI：
10.1007/s41105-017-0112-z
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发表时间：
2017
影响因子：
1.1
通讯作者：
Shimizu T.
中科院分区：
文献类型：
--
作者：
Suda H.;Kanbayashi T.;Ito S. U.;Sagawa Y.;Imanishi A.;Tsutsui Ko;Takahashi J.;Kikuchi Y.;Takahashi Y.;Shimizu T.
运动员可能会使用催眠药来避免睡眠障碍或体育赛事前一晚睡眠不足。然而，在过去，服用催眠药治疗睡眠障碍由于残留效应而导致不成功的尝试。本研究的目的是评估右佐匹克隆（2 mg），一种非苯二氮卓类催眠药，对12名健康运动员的身体表现，心理功能和主观评价的残留影响。右佐匹克隆在运动评估中没有严重的副作用。这种药物显着改善短期记忆测试，而不是安慰剂，并没有损害运动员的任何其他客观评价。在右佐匹克隆治疗期间，第二天的幸福感和疲劳量表没有变化，但主观评价中的日间警觉性显著恶化。当给予健康成人时，右佐匹克隆在第二天具有催眠活性，而不会干扰精神和身体表现，这表明右佐匹克隆可用于健康运动员，以调节其外在睡眠障碍及其连续的精神和身体障碍。
Hypnotics may be used by athletes to avoid sleep disturbance or insufficient sleep the night before sports events. However, in the past, taking hypnotics for sleep disturbances resulted in an unsuccessful attempt due to residual effects. The purpose of this study is to assess the residual effects of eszopiclone (2 mg), one of the non-benzodiazepine hypnotics, on physical performance, psychomotor function and subjective evaluations in 12 healthy athletes. Eszopiclone did not have serious side effects in athletic evaluations. This medication significantly improved short-term memory test rather than placebo and did not impair any other objective evaluations in athletes. There was no change in well-being and fatigue scales on the following day in the eszopiclone session, but daytime alertness was significantly worsened in the subjective evaluations. Eszopiclone has a hypnotic activity without disturbing psychomotor and physical performance on the following day when given to healthy adults, suggesting eszopiclone may be used in healthy athletes to adjust their extrinsic sleep disturbances and their consecutive psychomotor and physical impairments.