Liver ablation guidance with acoustic radiation force impulse imaging: challenges and opportunities
Liver ablation guidance with acoustic radiation force impulse imaging: challenges and opportunities
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DOI：
10.1088/0031-9155/51/15/013
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发表时间：
2006-08-07
影响因子：
3.5
通讯作者：
Trahey, G. E.
中科院分区：
文献类型：
--
作者：
Fahey, B. J.;Hsu, S. J.;Trahey, G. E.
先前的研究已经确定了声辐射力脉冲（ARFI）成像监测射频（RF）消融术的可行性。然而，关于该技术在临床现实场景中的实用性以及与成人腹部成像相关的扫描深度，仍存在问题。我们解决了其中的几个问题，并详细介绍了ARFI技术的临床相关性的最新进展。结果从体外牛组织和在体内绵羊模型。为了进一步支持该方法的临床可行性，使用组织模拟体模和并行接收跟踪技术进行了额外的实验。射频消融期间产生的热损伤在体外和体内肝组织中以高对比度可视化，并且可以在整个手术期间监测径向损伤生长。ARFI成像是在诊断超声扫描仪上实现的，因此可能是引导射频消融手术的方便选择，特别是当电极插入也在超声引导下进行时。
Previous studies have established the feasibility of monitoring radiofrequency (RF) ablation procedures with acoustic radiation force impulse (ARFI) imaging. However, questions remained regarding the utility of the technique in clinically realistic scenarios and at scanning depths associated with abdominal imaging in adults. We address several of these issues and detail recent progress towards the clinical relevance of the ARFI technique. Results from in vitro bovine tissues and an in vivo ovine model are presented. Additional experiments were conducted with a tissue-mimicking phantom and parallel receive tracking techniques in order to further support the clinical feasibility of the method. Thermal lesions created during RF ablation are visualized with high contrast in both in vitro and in vivo hepatic tissues, and radial lesion growth can be monitored throughout the duration of the procedure. ARFI imaging is implemented on a diagnostic ultrasonic scanner, and thus may be a convenient option to guide RF ablation procedures, particularly when electrode insertion is also performed with sonographic guidance.