3D-Mesa "Bridge" Silicon Microdosimeter: Charge Collection Study and Application to RBE Studies in 12C Radiation Therapy
3D-Mesa "Bridge" Silicon Microdosimeter: Charge Collection Study and Application to RBE Studies in 12C Radiation Therapy
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DOI：
10.1109/tns.2015.2391102
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发表时间：
2015-04-01
影响因子：
1.8
通讯作者：
Rosenfeld, Anatoly B.
中科院分区：
文献类型：
--
作者：
Tran, Linh T.;Chartier, Lachlan;Rosenfeld, Anatoly B.
微剂量学是一种非常有用的技术，用于空间和航空典型的未知混合辐射场的剂量学，以及强子治疗。针对传统的组织等效正比计数器的不足，提出了一种新型的三维敏感体硅微剂量计。利用ANSTO重离子微探针，研究了一种新型三维梅萨微剂量计的电荷收集特性。微剂量特性的测量允许在日本千叶的重离子医用加速器（HIMAC）上确定C-12重离子治疗束的相对生物学有效性。定义明确的敏感体积的3D梅萨微剂量计已被观察到和微剂量RBE得到表现出良好的协议与TEPC。新的3D梅萨“桥”微剂量计是朝着完全独立的3D敏感体积的微剂量计迈出的一步。
Microdosimetry is an extremely useful technique, used for dosimetry in unknown mixed radiation fields typical of space and aviation, as well as in hadron therapy. A new silicon microdosimeter with 3D sensitive volumes has been proposed to overcome the shortcomings of the conventional Tissue Equivalent Proportional Counter. In this article, the charge collection characteristics of a new 3D mesa microdosimeter were investigated using the ANSTO heavy ion microprobe utilizing 5.5 MeV He2+ and 2 MeV H+ ions. Measurement of the microdosimetric characteristics allowed for the determination of the Relative Biological Effectiveness of the C-12 heavy ion therapy beam at the Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan. Well-defined sensitive volumes of the 3D mesa microdosimeter have been observed and the microdosimetric RBE obtained showed good agreement with the TEPC. The new 3D mesa "bridge" microdosimeter is a step forward towards a microdosimeter with fully free-standing 3D sensitive volumes.