Development of a novel temporary epicardial pacing wire with biodegradable film.
Development of a novel temporary epicardial pacing wire with biodegradable film.
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DOI：
10.1016/j.athoracsur.2006.04.040
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发表时间：
2006-10
期刊：
影响因子：
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通讯作者：
Y. Narita;Yukako Fukuhira;H. Kagami;Eiichi Kitazono;Hiroaki Kaneko;Y. Sumi;A. Usui;M. Ueda;Y. Ueda
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文献类型：
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作者：
Y. Narita;Yukako Fukuhira;H. Kagami;Eiichi Kitazono;Hiroaki Kaneko;Y. Sumi;A. Usui;M. Ueda;Y. Ueda
PURPOSEA临时心外膜起搏钢丝(TEPW)已被常规放置在心脏手术患者身上。然而，它的固定或移除有时会引起麻烦的并发症。本研究的目的是开发一种新型的TEPW，使用可生物降解的薄膜将电极固定在心外膜上，而不需要针刺。描述：用聚(L-丙交酯-co-ϵ-己内酯)制备了可生物降解的薄膜。该膜具有蜂窝图案的结构，作为心肌表面的临时粘合剂，电极被结合在膜中。将新型TEPW放置于犬的心外膜上(A组，n=5)。对照组(B组，n=6)植入常规TEPW。分别于术后第0、1、3、5、7、14天测量起搏阈值、R波波幅、阻抗和转换率，并观察术后并发症，比较两组起搏阈值、R波幅度、阻抗和转换率的差异。结论新型TEPW用于心脏手术后管理是安全可行的。
PURPOSEA temporary epicardial pacing wire (TEPW) has been routinely placed in patients undergoing cardiac surgery. However, its fixation or removal occasionally causes troublesome complications. The aim of this study is to develop a novel TEPW using biodegradable film to fix the electrode to the epicardium without needle stabbing. DESCRIPTION: A biodegradable film was prepared with poly(L-lactide-co-ϵ-caprolactone). The film has a honeycomb-patterned structure that serves as a temporary adhesive for the myocardial surface, and the electrode was incorporated within the film. The novel TEPW was placed on the ventricular epicardium of dogs (group A, n = 5). As a control, conventional TEPW was inserted (group B, n = 6). The pacing threshold, R wave amplitude, impedance, and slew rate were measured at postoperative days 0, 1, 3, 5, 7, and 14, and complications after removal were checked.EVALUATIONAll measurements in both groups were identified and differences were not observed. In addition, the novel TEPWs could be easily removed without related complications.CONCLUSIONSThis novel TEPW is safe and feasible for postoperative management of cardiac surgeries.