Ruthenium- and platinum-catalyzed sequential reactions: selective synthesis of fused polycyclic compounds from propargylic alcohols and alkenes.
Ruthenium- and platinum-catalyzed sequential reactions: selective synthesis of fused polycyclic compounds from propargylic alcohols and alkenes.
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DOI：
10.1021/ja045532k
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发表时间：
2004-11
影响因子：
15
通讯作者：
Y. Nishibayashi;M. Yoshikawa;Youichi Inada;M. Hidai;S. Uemura
中科院分区：
文献类型：
--
作者：
Y. Nishibayashi;M. Yoshikawa;Youichi Inada;M. Hidai;S. Uemura
本文报道了一种简单的制备稠合多环化合物的方法，该方法是通过炔丙醇在合适的位置上进行分子内环化反应来实现的，其中Ru和Pt催化剂的存在促进了在相同介质中的一系列催化循环。该序列体系可用于炔丙醇与烯烃的分子间反应，得到相应的双环[3，1，0]己-2-烯衍生物。这些顺序反应提供了一种概念上新型的炔丙醇和烯烃之间的环加成体系。
A simple method for the preparation of fused polycyclic compounds by an intramolecular cyclization of propargylic alcohols bearing an alkene moiety at a suitable position has been developed, where the presence of both Ru and Pt catalysts promotes a sequence of catalytic cycles in the same medium. This sequential system can be applied to an intermolecular reaction between a propargylic alcohol and an alkene to obtain the corresponding bicyclo[3,1,0]hex-2-ene derivative. These sequential reactions provide a conceptually new type of cycloaddition system between propargylic alcohols and alkenes.