Palladium-catalyzed Benzylic Substitution of Benzyl Carbonates with Phosphorus Nucleophiles
Palladium-catalyzed Benzylic Substitution of Benzyl Carbonates with Phosphorus Nucleophiles
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DOI：
10.1246/cl.170901
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发表时间：
2017-10
影响因子：
1.6
通讯作者：
Y. Makida;Kazumi Usui;S. Ueno;R. Kuwano
中科院分区：
文献类型：
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作者：
Y. Makida;Kazumi Usui;S. Ueno;R. Kuwano
在钯催化剂 [Pd(η3-烯丙基)Cl]2-DPEphos 存在下，多种碳酸苄酯与膦酸二甲酯或氧化二苯基膦反应，以高产率生成苄基膦酸二甲酯和氧化苄基二苯基膦。催化膦酰化应用于从苄酯一锅合成烯烃。
A wide range of benzyl carbonates reacted with dimethyl phosphonate or diphenylphosphine oxide in the presence of the palladium catalyst, [Pd(η3-allyl)Cl]2–DPEphos, to give dimethyl benzylphosphonates and benzyldiphenylphosphine oxides in high yields. The catalytic phosphonylation was applied to the one-pot synthesis of alkenes from the benzyl esters.