Phytochrome A Mediates the Disassembly of Processing Bodies in Far-Red Light.
Phytochrome A Mediates the Disassembly of Processing Bodies in Far-Red Light.
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DOI：
10.3389/fpls.2022.828529
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发表时间：
2022
影响因子：
5.6
通讯作者：
Hiltbrunner A
中科院分区：
文献类型：
--
作者：
Schwenk P;Hiltbrunner A
光敏色素是控制植物生长和发育的红光和远红光受体，使它们能够对不断变化的光照条件做出充分的反应。研究表明，储存在称为加工体的 RNA 颗粒中的停止的 mRNA 在光感知时释放，有助于适应光环境。然而，这一过程的光生理背景在很大程度上尚不清楚。我们发现不同波长的光可以以剂量和时间依赖的方式触发加工体的分解。我们证明光敏色素在红光和远红光下控制这一过程，并且细胞质光敏色素 A 对于远红光诱导的加工体分解是充分且必要的。这为光敏色素 A 控制的过程增加了一种新颖的、意想不到的细胞质功能。总的来说，我们的研究结果表明光敏色素在控制储存在加工体中的翻译停止的 mRNA 中发挥着作用。我们希望我们的发现能够促进理解光和环境线索如何控制加工体的组装和拆卸，这可能对一般非膜细胞器的调节产生更广泛的影响。
Phytochromes are red- and far-red light receptors that control the growth and development of plants, enabling them to respond adequately to changing light conditions. It has been shown that halted mRNAs stored in RNA granules called processing bodies are released upon light perception and contribute to the adaptation to the light environment. However, the photophysiological background of this process is largely unknown. We found that light of different wavelengths can trigger the disassembly of processing bodies in a dose- and time-dependent manner. We show that phytochromes control this process in red- and far-red light and that cytoplasmic phytochrome A is sufficient and necessary for the far-red light-induced disassembly of processing bodies. This adds a novel, unexpected cytoplasmic function to the processes controlled by phytochrome A. Overall, our findings suggest a role of phytochromes in the control of translationally halted mRNAs that are stored in processing bodies. We expect our findings to facilitate understanding of how light and environmental cues control the assembly and disassembly of processing bodies, which could have broader implications for the regulation of non-membranous organelles in general.
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影响因子：
4.5
作者：
Genoud, Thierry;Schweizer, Fabian;Tscheuschler, Anke;Debrieux, Dimitry;Casal, Jorge J.;Schaefer, Eberhard;Hiltbrunner, Andreas;Fankhauser, Christian
通讯作者：
Fankhauser, Christian
影响因子：
18
作者：
Klose, Cornelia;Venezia, Filippo;Fleck, Christian
通讯作者：
Fleck, Christian
影响因子：
4
作者：
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通讯作者：
Shav-Tal, Yaron
影响因子：
7.2
作者：
Huq, E;Al-Sady, B;Quail, PH
通讯作者：
Quail, PH
CCR4 相关因子 1 的拟南芥同源物显示 mRNA 去腺苷酸化活性，并在植物防御反应中发挥作用
影响因子：
44.1
作者：
Liang, Wenxing;Li, Changbao;Li, Chuanyou
通讯作者：
Li, Chuanyou