Isolation of Adult Stem Cells from the Human Olfactory Mucosa
Isolation of Adult Stem Cells from the Human Olfactory Mucosa
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DOI：
10.1007/978-1-62703-574-3_10
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发表时间：
2013-01-01
期刊：
影响因子：
--
通讯作者：
Mackay-Sim, Alan
中科院分区：
文献类型：
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作者：
Feron, Francois;Perry, Chris;Mackay-Sim, Alan
位于鼻腔中的嗅粘膜是暴露于外部环境的唯一神经组织，并且在每个活着的个体中容易接近。此外，这个器官是一个持续的神经发生的家园，由大量的干细胞维持。在这里，我们描述了一种方法，从人类鼻腔嗅粘膜活检和分离多能成体干细胞，可用于识别大脑疾病的生物标志物或修复病理/创伤的神经系统。
The olfactory mucosa, located in the nasal cavity, is the only nervous tissue that is exposed to the external environment and easily accessible in every living individual. In addition, this organ is home of a continuing neurogenesis that is sustained by a large population of stem cells. Here, we describe a method for biopsy of olfactory mucosa from human nasal cavities and isolating multipotent adult stem cells that can be used to either identify biomarkers in brain disorders or repair the pathological/traumatized nervous system.