Narrow-band Imaging Digital Flexible Ureteroscopy in Detection of Upper Urinary Tract Transitional-Cell Carcinoma: Initial Experience
Narrow-band Imaging Digital Flexible Ureteroscopy in Detection of Upper Urinary Tract Transitional-Cell Carcinoma: Initial Experience
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DOI：
10.1089/end.2009.0593
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发表时间：
2011-01-01
影响因子：
2.7
通讯作者：
Al-Qahtani, Saeed M.
中科院分区：
文献类型：
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作者：
Traxer, Olivier;Geavlete, Bogdan;Al-Qahtani, Saeed M.
目的：为了表征使用新的URF-V数字输尿管软镜（DFU）进行窄带成像（NBI）时正常和恶性上尿路病变外观的外观，并确定NBI与白色光（WL）结合使用时是否可以提高恶性肿瘤的检测。患者和方法：27例患者在我校教学医院接受了NBI和WL，其中14例为已知的上尿路移行细胞癌（UUT-TCC）患者作为随访（A组），B组13例。由一名泌尿科医生首先在WL下进行肾集合系统检查，然后在NBI下进行肾集合系统检查。使用活检钳从所有检测到的病变中采集活检标本，并由对病变的大体描述不知情的病理学家进行检查。然后将病理解释与相应的WL和NBI图像进行比较。钬激光汽化进行所有明显的lesions.Results：主观上，NBI显着提高了内窥镜可视化的肿瘤，提供了一个详细的描述，他们的限制和血管结构。客观地，五个额外的肿瘤（14.2%）在四名患者，以及三个肿瘤（8.5%）在三名患者的扩展限制NBI检测时，WL成像结果被认为是normal.Conclusion：这是关于NBI的UUT-TCC的第一份报告之一。从这项研究中，我们推荐这项技术作为一种有价值的诊断方法，因为它大大提高了肿瘤的检出率为22.7%相比，WL。
Purpose: To characterize the appearance of normal and malignant upper urinary tract lesion appearance under narrow-band imaging (NBI) using the new URF-V digital flexible ureteroscope (DFU), and to determine if NBI, when used in conjunction with white light (WL), could improve detection of malignancy.Patients and Methods: NBI and WL were performed in 27 patients at our university teaching hospital, 14 with known cases of upper urinary tract transitional-cell carcinoma (UUT-TCC) as follow-up (group A), and 13 patients with first-suspicion of cancer (group B). Full renal collecting system examination was performed first under WL and then under NBI by a single urologist. Biopsies were taken from all detected lesions using the biopsy forceps and sent for examination by a pathologist who was blinded to the gross description of the lesion. Pathology interpretations were then compared with the corresponding WL and NBI images. Holmium laser vaporization was performed for all apparent lesions.Results: Subjectively, NBI significantly improved the endoscopic visualization of the tumors, providing a detailed description of their limits and vascular architecture. Objectively, five additional tumors (14.2%) in four patients, as well the extended limits of three tumors (8.5%) in three patients were detected by NBI when findings by WL imaging were considered normal.Conclusion: This is one of the first reports regarding NBI for UUT-TCC. From this study, we recommend this technology as a valuable diagnostic method, because it considerably improves tumor detection rate by 22.7% compared with WL.