INCREASED INTRADERMAL PROBING TIME IN SPOROZOITE-INFECTED MOSQUITOS
INCREASED INTRADERMAL PROBING TIME IN SPOROZOITE-INFECTED MOSQUITOS
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DOI：
10.4269/ajtmh.1984.33.17
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发表时间：
1984-01-01
影响因子：
3.3
通讯作者：
SPIELMAN, A
中科院分区：
文献类型：
--
作者：
ROSSIGNOL, PA;RIBEIRO, JMC;SPIELMAN, A
因为疟疾子孢子会破坏病媒蚊子的唾液腺部分。确定唾液功能的损害。这种病理会导致长时间的皮内探测阶段的进食行为，因为唾液的作用是帮助定位血管。未感染的埃及伊蚊蚊子探测的时间比子孢子感染或唾液剥夺的蚊子短。唾液腺苷三磷酸双磷酸酶活性在子孢子成熟后降低至第三。腺苷三磷酸双磷酸酶活性通常局限于被子孢子侵入的那些区域。子孢子感染和未感染的蚊子产生相同体积的唾液。显然，子孢子感染通过影响唾液产物的质量增加潜在的感染性宿主接触而损害载体定位血管的能力。
Because malaria sporozoites destroy segments of the salivary glands of vector mosquitoes. The impairment of salivary function was determined. Such pathology would result in a prolonged intradermal probing phase of feeding behavior, because the role of saliva is to help locate blood vessels. Noninfected Aedes aegypti mosquitoes probed for a shorter period than did either sporozoite-infected or saliva-deprived mosquitoes. Salivary apyrase activity is reduced to a 3rd following maturation of sporozoites. Apyrase activity is normally confined to those regions invaded by sporozoites. Sporozoite-infected and noninfected mosquitoes produced equal volumes of saliva. Apparently, sporozoite infection impairs the vector''s ability to locate blood vessels by affecting the quality of salivary product increasing potentially infective host contacts.