Accounting for the ATP-consuming processes in rabbit reticulocytes.
Accounting for the ATP-consuming processes in rabbit reticulocytes.
复制标题
考虑兔网织红细胞中 ATP 消耗过程。
DOI：
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
S. Rapoport
中科院分区：
文献类型：
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作者：
W. Siems;W. Dubiel;R. Dumdey;M. Müller;S. Rapoport
本报告详细论述了家兔网织红细胞ATP产生和消耗的平衡。产生的ATP总量为135 mmol。1-1 . h-1。约70%的ATP消耗是由特定过程产生的。主要的贡献过程是珠蛋白合成（约28%）、Na+，K+-ATP酶（约23%）和蛋白质水解（约15%）。30%的ATP消耗量尚未计算在内。环己酰亚胺（20 μ M）导致蛋白质的合成和降解之间的解离，这反对这些过程之间的任何必然联系。超过90%的赖氨酸从线粒体释放的蛋白水解被重新利用的球蛋白的合成，证明高氮经济的网织红细胞。研究的每个ATP消耗过程似乎都以独立的方式控制ATP的产生，彼此之间没有竞争。
The report deals with a detailed balance of ATP production and consumption of the rabbit reticulocyte. The sum-total of ATP produced amounts to 135 mmol . 1-1 . h-1. About 70% of the ATP consumption has been accounted for by specific processes. The main contributing processes are the globin synthesis with about 28%, the Na+, K+-ATPase with 23% and the proteolysis with more than 15%. 30% of ATP consumption has not been accounted for. Cycloheximide (20 microM) leads to a dissociation between synthesis and degradation of proteins, which argues against any obligatory connection between these processes. More than 90% of the lysine liberated from mitochondria by proteolysis were reutilized for the globin synthesis demonstrating the high nitrogen economy of reticulocytes. Each of the ATP-consuming processes studied appears to control ATP production in an independent manner without competition with each other.
人红细胞中的谷胱甘肽周转率。
DOI：
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发表时间：
1981
期刊：
The Journal of biological chemistry
影响因子：
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作者：
Griffith,OW
通讯作者：
Griffith,OW