Segmented simultaneous multi-slice diffusion weighted imaging with generalized trajectories.

Segmented simultaneous multi-slice diffusion weighted imaging with generalized trajectories.
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DOI:
10.1002/mrm.26545
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发表时间:
2017-10
影响因子:
3.3
通讯作者:
Stenger VA
Stenger VA
中科院分区:
医学3区
文献类型:
--
作者:
Herbst M;Deng W;Ernst T;Stenger VA

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这项工作的目的是开发和评估一个单一的框架,使用笛卡尔和非笛卡尔分割轨迹快速和强大的同时多层面(SMS)扩散加权成像(DWI)在3T。提出了一种基于多路灵敏度编码(MUSE)的内相导航广义SMS方法。使用32通道头部线圈在3T下使用SMS DWI扫描检查分段翻转CAIPI回波平面成像(EPI)和z梯度调制螺旋轨迹。广义SMS MUSE重建框架在显著减少所有轨迹的伪影方面是成功的。DWI脑体积与67.5毫米的高度,1.5毫米的各向同性分辨率,和90个扩散加权在6分钟的扫描时间。MUSE技术可以推广到允许笛卡尔和非笛卡尔分段轨迹的重建。
The purpose of this work is to develop and evaluate a single framework for the use of Cartesian and non-Cartesian segmented trajectories for rapid and robust simultaneous multi-slice (SMS) diffusion-weighted imaging (DWI) at 3T. A generalized SMS approach with intrinsic phase navigation using Multiplexed Sensitivity Encoding (MUSE) was developed. Segmented blipped-CAIPI Echo Planar Imaging (EPI) and z-gradient modulated spiral trajectories were examined using SMS DWI scans at 3T with a 32-channel head coil. The generalized SMS MUSE reconstruction framework was successful in significantly reducing artifacts for all trajectories. A DWI brain volume with a 67.5 mm height, 1.5 mm isotropic resolution, and 90 diffusion weightings was obtained in a scan time of six minutes. The MUSE technique can be generalized to allow for reconstruction of both Cartesian and non-Cartesian segmented trajectories.