Association between serum osteocalcin level and visceral obesity in Chinese postmenopausal women
Association between serum osteocalcin level and visceral obesity in Chinese postmenopausal women
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中国绝经后女性血清骨钙素水平与内脏肥胖的关系
DOI：
10.1111/cen.12793
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发表时间：
2015-09-01
影响因子：
3.2
通讯作者：
Jia, Weiping
中科院分区：
文献类型：
--
作者：
Luo, Yuqi;Ma, Xiaojing;Jia, Weiping
背景低血清骨钙素水平、内脏肥胖和绝经状态是公认的心血管疾病的危险因素。我们研究了中国绝经后妇女血清骨钙素水平和内脏脂肪含量之间的关系。设计和患者共1481名绝经后妇女，（平均年龄57 ± 148岁，标准差57 ± 148岁），采用磁共振成像定量腹部脂肪堆积。内脏脂肪面积（VFA）80 cm（2）的受试者被归类为腹部肥胖。结果血清骨钙素水平中位数为2066 g/l（四分位数范围1688- 2542 g/l）。腹型肥胖的总患病率为491%（n=727）。腹型肥胖者血清骨钙素水平低于非腹型肥胖者[分别为1914（1602-2382）vs 2197（1814-2677）g/l; P
BackgroundA low serum osteocalcin level, visceral obesity and postmenopausal status are recognized risk factors for cardiovascular disease.ObjectiveWe investigated the relationship between the serum osteocalcin level and visceral fat content in a population of Chinese postmenopausal women.Design and patientsIn total, 1481 postmenopausal women (mean agestandard deviation, 57148years) were selected from the Shanghai Obesity Study.MeasurementsAbdominal fat accumulation was quantified using magnetic resonance imaging. Subjects with a visceral fat area (VFA) of 80cm(2) were classified as abdominally obese. The total serum osteocalcin level was measured by electrochemiluminescence immunoassay.ResultsThe median serum osteocalcin level was 2066g/l (interquartile range, 1688-2542g/l). The overall prevalence of abdominal obesity was 491% (n=727). Abdominally obese subjects had lower serum osteocalcin levels than did nonabdominally obese subjects [1914 (1602-2382) vs 2197 (1814-2677) g/l, respectively; P