Disparate requirement for T cells in resistance to mucosal and acute systemic candidiasis
Disparate requirement for T cells in resistance to mucosal and acute systemic candidiasis
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DOI：
10.1128/iai.68.4.2363-2365.2000
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发表时间：
2000-04-01
影响因子：
3.1
通讯作者：
Balish, E
中科院分区：
文献类型：
--
作者：
Jones-Carson, J;Vazquez-Torres, A;Balish, E
虽然对口胃念珠菌病高度敏感，但发现分别缺乏γ δ和α β T细胞的T细胞受体δ和α链敲除小鼠对内源性播散性念珠菌病和急性全身性念珠菌病（静脉注射所致）具有抗性。
Although highly susceptible to orogastric candidiasis, T-cell receptor delta- and alpha-chain knockout mice, deficient in gamma delta and alpha beta T cells, respectively, were found to be resistant to disseminated candidiasis of endogenous origin and to acute systemic candidiasis (resulting from intravenous injection).