Palladium-catalyzed direct intermolecular silylation of remote unactivated C(sp(3))-H bonds.
Palladium-catalyzed direct intermolecular silylation of remote unactivated C(sp(3))-H bonds.
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钯催化远程未活化 C(sp(3))-H 键的直接分子间硅烷化。
DOI：
10.1039/c6cc07885k
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Zhang Shu-Yu
中科院分区：
文献类型：
--
作者：
Pan Jin-Long;Li Quan-Zhe;Zhang Ting-Yu;Hou Si-Hua;Kang Jun-Cheng;Zhang Shu-Yu
发展了一种有效和方便的方法来实现未活化的远程伯或仲C（sp3）-H键与六甲基二硅烷（HMDS）的直接硅烷化以形成C-Si键。该方法突出了在有机合成中将未活化的甲基或亚甲基转化为多功能基团的新兴策略，并为合成化学提供了构建功能化C-Si键的新方法。
An efficient and convenient method has been developed to achieve direct silylation of unactivated remote primary or secondary C(sp3)–H bonds to form C–Si bonds with hexamethyldisilane (HMDS). This method highlights the emerging strategy to transform unactivated methyl or methylene into versatile functional groups in organic synthesis and provides a new method to construct functionalized C–Si bonds for synthetic chemistry.