Is alexithymia a risk factor for major depression, personality disorder, or alcohol use disorders? A prospective population-based study
Is alexithymia a risk factor for major depression, personality disorder, or alcohol use disorders? A prospective population-based study
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DOI：
10.1016/j.jpsychores.2009.05.010
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发表时间：
2010-03-01
影响因子：
4.7
通讯作者：
Viinamaki, Heimo
中科院分区：
文献类型：
--
作者：
Honkalampi, Kirsi;Koivumaa-Honkanen, Heli;Viinamaki, Heimo
目的：关于述情障碍的稳定性及其预测后续精神障碍的能力存在分歧。这项为期7年的随访研究的目的是检查述情障碍是否预测后续的重性抑郁症、人格障碍。或酒精使用障碍。研究方法：库奥皮奥抑郁症研究（Kuopio Depression Study，KUDEP）在芬兰中部芬兰中部进行。研究人群（25-64岁，n=2050）从国家人口登记处随机抽取。数据收集于1998年、1999年和2001年。2005年，收集了3年随访尖端人群（1998-2001年）的子样本（n=333，排除43），并诊断为精神障碍。经DSM-IV轴I（SCID-1）结构临床访谈证实。使用多伦多述情障碍量表（TAS-20）测量述情障碍，使用贝克抑郁量表（BDI-21）测量抑郁症状。对于这两种测量方法，根据其总分的中位数（将1998年、1999年和2001年的得分相加）分为两组。结果如下：2005年，BDI总分与继发性重性抑郁障碍、人格障碍和酒精使用障碍相关，TAS总分与继发性重性抑郁障碍、人格障碍和酒精使用障碍无关。BDI总分解释了同期TAS总分变异的35.7%。结论：述情障碍不能预测抑郁症、人格障碍或酒精使用障碍的诊断，述情障碍与并发抑郁症状密切相关。因此，抑郁症状可能是述情障碍与精神病发病率之间的中介。(C)2010爱思唯尔公司版权所有
Objective: Disagreements concerning the stability of alexithymia and its ability to predict Subsequent psychiatric disorders prevail The ann of this 7-year follow-tip study was to examine whether alexithymia predicts Subsequent major depression, personality disorder. or alcohol use disorders in a population-based sample. Methods: The four-phase Kuopio Depression Study (KUDEP) was conducted in the eastern part of Central Finland The study population (aged 25-64, n=2050) was randomly selected from the National Population Register. Data were collected in 1998, 1999,and 2001 In 2005, a subsample (n=333, 43 were excluded) of the 3-year follow-tip population (1998-2001) was gathered and their diagnoses of mental disorders. were confirmed by the Structure Clinical Interview for DSM-IV Axis I (SCID-1). Alexithymia was measured using the Toronto Alexithymia Scale (TAS-20) and depressive symptoms using the Beck Depression Inventory (BDI-21) For both of these measures, two groups were formed based on the median of their sum score (summing the 1998, 1999, and 2001 scores) Logistic regression analyses were performed. Results: BDI sum scores, but not those of TAS, were associated With Subsequent major depressive disorder, personality disorder, and alcohol use disorders in 2005. The BDI sum scores explained 35.7% of the variation in concurrent TAS sum scores. Conclusion: Alexithymia did not predict diagnoses of major depressive disorder, personality disorder, or alcohol use disorders Alexithymia was closely linked to concurrent depressive symptoms Thus, depressive symptoms may act as a mediator between alexithymia and psychiatric morbidity. (C) 2010 Elsevier Inc All rights reserved