Galactosialidosis: Low β‐galactosidase activity in serum after long‐term clotting
Galactosialidosis: Low β‐galactosidase activity in serum after long‐term clotting
复制标题
半乳糖唾液酸贮积症：长期凝血后血清中β-半乳糖苷酶活性低
DOI：
10.1002/ana.410180215
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发表时间：
1985
影响因子：
11.2
通讯作者：
M. Akagi
中科院分区：
文献类型：
--
作者：
H. Sakuraba;Y. Iimori;Yoshiyuki Suzuki;J. Kint;M. Akagi
在正常受试者的凝血中发现血清β-半乳糖苷酶活性显著增加，但半乳糖唾液酸沉积症患者仅显示该酶活性轻微增加。因此，患有这种疾病的患者在长期凝血后血清中的β-半乳糖苷酶活性较低。酶的激活机制尚不清楚。抗凝剂的使用完全抑制了激活。
Serum β‐galactosidase activity was found to be markedly increased in clotting blood from normal subjects, but patients with galactosialidosis showed only a slight increase of this enzyme activity. Consequently, the β‐galactosidase activity was low in serum after long‐term clotting in patients with this disease. The mechanism of the enzyme activation is unknown. The use of anticoagulants completely inhibited the activation.