THE IN-VITRO RELEASE OF PROTHORACICOTROPIC HORMONE (PTTH) FROM THE BRAIN CORPUS CARDIACUM CORPUS ALLATUM COMPLEX OF SILKWORM, BOMBYX-MORI
THE IN-VITRO RELEASE OF PROTHORACICOTROPIC HORMONE (PTTH) FROM THE BRAIN CORPUS CARDIACUM CORPUS ALLATUM COMPLEX OF SILKWORM, BOMBYX-MORI
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DOI：
10.1016/0742-8413(94)00101-f
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发表时间：
1995-02-01
期刊：
影响因子：
--
通讯作者：
AIZONO, Y
中科院分区：
文献类型：
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作者：
SHIRAI, Y;SHIMAZAKI, K;AIZONO, Y
开发了一种体外系统，用于评估家蚕脑-CC-CA 复合物中准确的 PTTH 释放。高钾离子浓度诱导的 PTTH 释放在 30 分钟内达到最大水平，并且取决于钾离子的浓度。 PTTH 的释放也依赖于钙离子，并由钙离子载体诱导，表明细胞内钙离子的增加可能对其释放至关重要。 Carhachol（乙酰胆碱激动剂）诱导 PTTH 释放最快，其次是多巴胺和血清素，而去甲肾上腺素则没有作用。卡巴胆碱可能在脑-CC-GA复合物的脑中起作用。
An in vitro system for evaluation of the exact PTTH release from the brain-CC-CA complex of Bontbyx mori was developed. The PTTH release induced with a high potassium ion concentration reached the maximal level in 30 min and was dependent on the concentration of the potassium ion. The PTTH release was also dependent on the calcium ion and was induced with a calcium ionophore, indicating that increasing intracellular calcium ion might be essential for its release. Carhachol (acetylcholine agonist) induced the PTTH release fastest, followed by dopamine and serotonin in that order, while norepinephrine exerted no effect. Carbachol might act in the brain of brain-CC-GA complex.