Acupuncture for systemic lupus erythematosus: a pilot RCT feasibility and safety study
Acupuncture for systemic lupus erythematosus: a pilot RCT feasibility and safety study
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DOI：
10.1177/0961203308093921
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发表时间：
2008-01-01
期刊：
影响因子：
2.6
通讯作者：
Manzi, S.
中科院分区：
文献类型：
--
作者：
Greco, C. M.;Kao, A. H.;Manzi, S.
本研究的目的是确定研究针灸治疗系统性红斑狼疮（SLE）患者的可行性，并初步测试旨在减轻疼痛和疲劳的标准化针灸方案的安全性和益处。24例SLE患者被随机分配接受10个疗程的针灸，微针或常规护理。在基线和最后一次治疗后评估疼痛、疲劳和SLE疾病活动。在每次会议上评估安全性。筛选了52例患者，招募了24名合格和感兴趣的人。虽然有短暂的副作用，如短暂的针刺疼痛和头晕，但没有严重的不良事件与针灸或最小针刺程序相关。22名参与者完成了研究，大多数（85%）针灸和最小针刺参与者能够在5-6周的指定时间内完成他们的疗程。40%接受针灸或最小针刺的患者在标准疼痛测量方面有>= 30“%的改善，但常规护理患者的疼痛有所改善。10个疗程的活动疗法对SLE患者是可行和安全的。针灸和最小针刺的好处是相似的。Lupus（2008）17，1108-1116.
The objective of this study was to determine the feasibility of studying acupuncture in patients with systemic lupus erythematosus (SLE), and to pilot test the safety and explore benefits of a standardized acupuncture protocol designed to reduce pain and fatigue. Twenty-four patients with SLE were randomly assigned to receive 10 sessions of either acupuncture, minimal needling or usual care. Pain, fatigue and SLE disease activity were assessed at baseline and following the last sessions. Safety was assessed at each session. Fifty-two patients were screened to enroll 24 eligible and interested persons. Although transient side effects, such as brief needling pain and lightheadedness, were reported, no serious adverse events were associated with either the acupuncture or minimal needling procedures. Twenty-two participants completed the study, and the majority (85%) of acupuncture and minimal needling participants were able to complete their sessions within the specified time period of 5-6 weeks. 40% of patients who received acupuncture or minimal needling had >= 30`% improvement on standard measures of' pain, but do usual care patients showed improvement in pain. A ten-session course Of' acttpttncture appears feasible and safe for patients with SLE. Benefits were similar for acupuncture and minimal needling. Lupus (2008) 17, 1108-1116.