Duration of overweight and metabolic health risk in American men and women
Duration of overweight and metabolic health risk in American men and women
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DOI：
10.1016/j.annepidem.2004.01.007
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发表时间：
2004-09-01
影响因子：
5.6
通讯作者：
Ross, R
中科院分区：
文献类型：
--
作者：
Janssen, I;Katzmarzyk, PT;Ross, R
目得：研究超重持续时间与代谢健康风险之间的关系。方法：受试者包括4874名参与者，年龄在30至64岁之间，来自第三次全国健康与营养检查调查。超重的持续时间是根据调查前10年的回忆体重确定的。代谢健康风险从空腹血液样本和血压measurements.RESULTS确定：调整当前的体重指数后，肥胖相关的合并症的相对几率并不高于男性谁已经超重< 10年与正常体重的男性相比。然而，与正常体重男性相比，超重10年的男性患高甘油三酯血症[2.39（1.34-4.27）]和代谢综合征[2.15（1.01-1.57）]的可能性[比值比（95%置信区间）]增加。在女性中，当从正常体重到超重< 10年到超重大于或等于10年的类别时，许多代谢紊乱的可能性呈分级增加（p < 0.001）。结论：超重的持续时间对男性和女性肥胖相关的合并症有显著影响。(C)2004年爱思唯尔公司All rights reserved.
PURPOSE: To investigate the association between overweight duration and metabolic health risk.METHODS: Subjects consisted of 4874 participants, aged 30 to 64 years, from the Third National Health and Nutrition Examination Survey. Duration of overweight was determined from recalled weights from 10 years prior to the survey. Metabolic health risk was determined from a fasting blood sample and blood pressure measurements.RESULTS: After adjusting for current body mass index, the relative odds for obesity-related comorbidities were not higher in men who had been overweight for < 10 years compared with men with a normal weight. However, the likelihood [odds ratios (95% confidence intervals)] of hypertriglyceridemia [2.39 (1.34-4.27)] and the metabolic syndrome [2.15 (1.01-1.57)] were increased in men who had been overweight for; 10 years compared with normal weight men. In women there was a graded increase (p < 0.001) in the likelihood of numerous metabolic disorders when moving from the normal weight to overweight < 10 year to overweight greater than or equal to 10 year categories.CONCLUSIONS: The duration of overweight has a significant effect on obesity-related comorbidities in men and women. (C) 2004 Elsevier Inc. All rights reserved.