Comparison of risk factors associated with sepsis between road traffic injuries and non-road traffic injuries in ICU patients with severe trauma
Comparison of risk factors associated with sepsis between road traffic injuries and non-road traffic injuries in ICU patients with severe trauma
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ICU严重创伤患者道路交通伤与非道路交通伤脓毒症相关危险因素比较
DOI：
10.4103/2221-6189.244166
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发表时间：
2018-09
期刊：
影响因子：
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通讯作者：
Liang HP
中科院分区：
文献类型：
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作者：
Ma XY;Jin HJ;Cheng SW;Tang WQ;Ma W;Luo L;Yang X;Wang Q;Wang B;Liang HP
目的：了解道路交通伤与非道路交通伤之间脓毒症的发生率及相关危险因素。方法：回顾分析2012-01/2015-12陆军军医大学第三附属医院和崇钢总医院ICU收治的339例严重创伤患者的临床资料。对影响脓毒症的20项潜在危险因素进行单因素和多因素Logistic分析，以比较RTI患者和非RTI患者之间的差异。结果：进入研究期的RTI患者154例，非RTI患者185例。呼吸道感染并发脓毒症的显著独立危险因素为SOFA 11(OR=4.821；95%CI=1.901~12.226；P=0.001)。非RTI患者发生脓毒症的显著独立危险因素为SOFA 11(OR=12.410；95%CI=2.559~60.185；P=0.002)、气管插管(OR=8.913；95%CI=2.322~34.206；P=0.001)、APACHE II 15(OR=3.684；95%CI=1.750~7.753；P=0.00)。结论：ICU内RTI患者与非RTI患者发生脓毒症的预测因素不同，临床医务人员不应一视同仁。样本量应该增加，并在进一步的前瞻性研究中得到验证。
Objective: To estimate the incidence and related risk factors of sepsis between road traffic injuries (RTIs) and non-RTIs. Methods: Clinical data of 339 patients with severe trauma who were admitted into ICU in both Third Affiliated Hospital of Army Military Medical University and ChongGang General Hospital from January 2012 to December 2015 were retrospectively analyzed. Twenty items of potential risk factors affecting sepsis were evaluated by univariate and multivariate Logistic Analysis with the purpose of drawing a comparison between RTI patients and non-RTI patients. Results: There were 154 cases of RTI and 185 cases of non-RTI entering the study period. The significant independent risk factor of sepsis in RTIs was SOFA 11 (OR=4.821; 95% CI=1.901-12.226; P=0.001). The significant independent risk factors of sepsis in non-RTIs were SOFA 11 (OR=12.410; 95% CI=2.559-60.185; P=0.002), tracheal intubation (OR=8.913; 95% CI=2.322-34.206; P=0.001), APACHE II 15 (OR=3.684; 95% CI=1.750-7.753; P=0.001). Conclusions: The clinical medical personnel should not give equal treatment to RTI patients and non-RTI patients admitted in ICU in that factors predicting sepsis within above two groups are different. The sample volume should be increased and validated in further prospective research.