Copper deficiency caused by excessive alcohol consumption.
Copper deficiency caused by excessive alcohol consumption.
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DOI：
10.1136/bcr-2017-220921
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发表时间：
2017-09-26
期刊：
影响因子：
0.9
通讯作者：
Taniuchi, Norihide
中科院分区：
文献类型：
--
作者：
Shibazaki, Shunichi;Uchiyama, Shuhei;Taniuchi, Norihide
铜缺乏是一种导致细胞减少和神经病变的疾病，可以通过补充铜来治疗。长期管饲，长期全胃肠外营养，肠切除和摄入锌是已知的铜缺乏症的危险因素;然而，酗酒不是。在这个病例中，一名71岁的男子难以醒来。他有每天喝五杯以上烈酒的历史。三个月前他还好好的。在他来我们医院的一个月前，他不能吃饭，但继续喝酒。他入院时患有巨红细胞性贫血。铜和铜蓝蛋白水平显着降低，我们诊断为铜缺乏症。没有其他已知的铜缺乏症风险因素。在他开始喝可可作为铜补充剂后，贫血得到了改善，他能够走路了。这是第一份报告显示酒精滥用是铜缺乏症的危险因素。
Copper deficiency is a disease that causes cytopaenia and neuropathy and can be treated by copper supplementation. Long-term tube feeding, long-term total parenteral nutrition, intestinal resection and ingestion of zinc are known copper deficiency risk factors; however, alcohol abuse is not. In this case, a 71-year-old man had difficulty waking. He had a history of drinking more than five glasses of spirits daily. He was well until 3 months ago. A month before his visit to our hospital, he could not eat meals but continued drinking. He had macrocytic anaemia on admission. Copper and ceruloplasmin levels were markedly low, and we diagnosed copper deficiency. There were no other known risk factors for copper deficiency. After he began drinking cocoa as a copper supplement, the anaemia ameliorated and he was able to walk. This is the first report showing alcohol abuse as a risk factor for copper deficiency.