Mesenteric venous thrombosis--1911 to 1984.
Mesenteric venous thrombosis--1911 to 1984.
复制标题
肠系膜静脉血栓形成——1911年至1984年。
作者：
R. Abdu;B. J. Zakhour;D. Dallis
本研究的目的是确定肠系膜静脉血栓形成（MVT）可能发生的患者，并回顾其病理生理学、临床表现、诊断方式和患者结局。我们回顾了1911年至1984年372例MVT患者的文献，其中包括5例我们自己的患者。其中99例患者的数据来自尸检报告，未纳入研究。这种疾病常见于生命的第六和第七个十年，其中81%的老年患者患有相关疾病。MVT累及小肠段，但很少累及结肠，表现为出血性梗死而非坏疽。这种疾病不符合一种模式，尽管前驱期几天或几周的腹痛（通常与体格检查不成比例）、明显的白细胞增多和脱水都高度提示MVT。通过腹膜穿刺获得的血清血性液体是一种有用的诊断工具。高度怀疑、早期诊断和及时手术干预并添加抗凝剂似乎可以提高生存率并减少复发。
The objective of this study was to identify those patients in whom mesenteric venous thrombosis (MVT) is likely to develop and to review the pathophysiology, clinical presentation, diagnostic modalities, and patient outcome. We present a review of the literature from 1911 to 1984 with respect to 372 patients with MVT, including five of our own patients. Data on 99 of these patients were obtained from autopsy reports and were not included in the study. This disease is common in the sixth and seventh decades of life, with 81% of these older patients having associated illnesses. MVT involves segments of the small bowel, but rarely of the colon, with hemorrhagic infarcts rather than gangrene. This disease does not conform to a pattern, although a prodromal period of days or weeks of abdominal pain (which is usually out of proportion to physical findings), marked leukocytosis, and dehydration are all highly suggestive of MVT. Serosanguineous fluid obtained by means of peritoneal tap is a useful diagnostic tool. A high index of suspicion, early diagnosis, and prompt surgical intervention with the addition of anticoagulants seems to improve survival and reduce recurrence.