Differences in treatment of acute myocardial infarction by sex, age, and other factors (the Stanford Five-City Project).

Differences in treatment of acute myocardial infarction by sex, age, and other factors (the Stanford Five-City Project).
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性别、年龄和其他因素对急性心肌梗死治疗的差异(斯坦福五城项目)。

DOI:
10.1016/s0002-9149(96)00457-2
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发表时间:
1996
期刊:
The American journal of cardiology
影响因子:
--
通讯作者:
Varady,AN
Varady,AN
中科院分区:
--
文献类型:
--
作者:
Oka,RK;Fortmann,SP;Varady,AN

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参考文献

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本研究调查了1986年至1992年期间参加斯坦福大学五城市项目的2,021名住院男性和995名年龄在30至74岁之间的女性急性心肌梗死(AMI)患者在血管造影术后进行血运重建手术的时间趋势。我们的样本包括出院诊断代码为410至414的住院患者,符合明确或可能的AMI的研究标准。纳入了1986年至1992年期间发生的偶发和复发性梗死,但仅纳入了每位患者在此期间的首次事件。我们进行了逐步多元Logistic回归分析,以确定:(1)接受冠状动脉造影,(2)通过冠状动脉旁路手术或血管成形术进行血管重建的可能性,以及(3)溶栓治疗。年龄、手术年份、疾病严重程度以及症状出现和药物治疗之间的时间作为协变量。在调整这些因素后,女性比男性更不可能接受血管造影术,但同样可能接受血运重建和溶栓治疗。西班牙裔和白人接受血管造影和溶栓治疗的可能性相同,但西班牙裔接受血运重建的可能性低于白人。年龄和疾病严重程度是冠状动脉造影的反向预测因子,但不是血运重建的反向预测因子。年龄、严重程度和症状发作与药物治疗之间的延迟时间是溶栓的反向预测因素;女性的延迟时间显著大于男性,男女平均>6小时。在研究期间,接受血管造影、血运重建和溶栓治疗的可能性急剧增加。(Am J Cardiol 1996;78:861-865)
This study examines the temporal trends in the use of angiography followed by revascularization procedures for acute myocardial infarction (AMI) in 2,021 hospitalized men and 995 women aged 30 to 74 years who participated in the Stanford Five-City Project during the years 1986 to 1992. Our sample included hospitalized patients who received a discharge diagnosis code of 410 through 414 and met study criteria for either a definite or possible AMI. Incident and recurrent infarctions occurring in the years 1986 through 1992 were included, but only the first event in this period for each patient. We performed stepwise multiple logistic regression analysis to determine the probability of: (1) receiving coronary angiography, (2) revascularization by either coronary bypass surgery or angioplasty among those with angiogram, and (3) thrombolytic therapy. Age, year of procedure, disease severity, and time between symptom onset and medical treatment were included as covariates. After adjustment of these factors, women were less likely than men to undergo angiography but were equally likely to undergo revascularization and thrombolysis. Hispanics and whites were equally likely to receive angiography and thrombolysis, but Hispanics were less likely than whites to undergo revascularization. Age and disease severity were inverse predictors of coronary angiography but not of revascularization. Age, severity, and delay time between onset of symptoms and medical therapy were inverse predictors of thrombolysis; delay time was significantly greater in women than in men and averaged >6 hours in both sexes. The likelihood of receiving angiography, revascularization, and thrombolysis increased sharply over the study period. (Am J Cardiol 1996;78:861–865)
DOI: --
发表时间: 1993
影响因子: 24
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影响因子: 2.8
作者:
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MARK, DB;SHAW, LK;PRYOR, DB
通讯作者: PRYOR, DB
DOI: 10.7326/0003-4819-107-1-19
发表时间: 1987-07-01
影响因子: 39.2
作者:
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女性冠状动脉溶栓。
DOI: --
发表时间: 1990
期刊: The Cardiology
影响因子: --
作者:
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通讯作者: R. Becker