Cattle-to-cattle transmission of Mycobacterium bovis
Cattle-to-cattle transmission of Mycobacterium bovis
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DOI：
10.1054/tube.2000.0256
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发表时间：
2001-01-01
期刊：
影响因子：
3.2
通讯作者：
Clifton-Hadley, RS
中科院分区：
文献类型：
--
作者：
Goodchild, AV;Clifton-Hadley, RS
本综述以英国 (GB) 感染牛分枝杆菌 (TB) 的牛群特征数据为例，试图确定结核病牛间传播 (CCT) 的作用。尽管与已确定的野生动物来源相比，CCT 的作用相对较小，但 CCT 通过购买受感染的动物或连续传播，在感染进入畜群中发挥了一定作用。实验研究表明，CCT 有可能在牛群内发生。 1999年，英国三分之二以上的确诊结核病事件中发现了不止一个反应堆。描述了从传染性动物到易感动物的传播细节：直接传播，这取决于接触的紧密程度和通风等因素；或间接传播，这也取决于宿主体外的生存情况。牛群规模是结核病发病的一个危险因素，无论是牛群还是个体牛。结核病的控制被认为与皮肤试验有关：试验未能将所有受感染的动物从事故中清除是可能的，但可能不如未能防止畜群外部来源的再感染那么重要。结论是CCT对于确定反应堆总数可能具有重要意义。保护牛群免受其他结核病来源的影响可能会减少 CCT 的副作用。 (C) 2001 年哈考特出版有限公司。
This review, illustrated with data on the characteristics of herds infected with Mycobacterium bovis (TB) in Great Britain (GB), attempts to identify the role of cattle-to-cattle transmission (CCT) of TB. CCT plays a part in the entry of infection into herds, through purchased infected animals or contiguous spread, although CCT can have a relatively small role in comparison with an established wildlife source. Experimental studies have shown that it is possible for CCT to occur within herds. In 1999, more than one reactor was found in over two-thirds of confirmed TB incidents in Great Britain. The details of transmission from an infectious animal to a susceptible animal are described: proximate, which depends on factors such as closeness of contact and ventilation, or indirect, which also depends on survival outside the host. Herd size is a risk factor for the incidence of TB, both in herds and in individual cattle. Control of TB is considered in relation to the skin test: failure of the test to remove all infected animals from incidents is possible, but probably of less significance than failure to prevent reinfection from sources external to the herd. It is concluded that CCT may have significance in determining the total number of reactors. Safeguarding herds from other sources of TB is likely to reduce CCT as a side effect. (C) 2001 Harcourt Publishers Ltd.