Malaria in China, 2011-2015: an observational study.
Malaria in China, 2011-2015: an observational study.
复制标题
DOI：
10.2471/blt.17.191668
复制
发表时间：
2017-08-01
影响因子：
11.1
通讯作者：
Yu H
中科院分区：
文献类型：
--
作者：
Lai S;Li Z;Wardrop NA;Sun J;Head MG;Huang Z;Zhou S;Yu J;Zhang Z;Zhou SS;Xia Z;Wang R;Zheng B;Ruan Y;Zhang L;Zhou XN;Tatem AJ;Yu H
[目的]了解2011年至2015年中国疟疾流行趋势、疟疾负担及干预费用。我们利用2011年至2015年的疟疾分类监测数据，覆盖了中国地区主要疟疾媒介范围，分析了本地传播和输入性疟疾病例的时空特征和人口学特征。根据资金来源、干预措施和高危人口计算了消灭疟疾的总成本和平均成本。内地中国共报告17例 745疟疾病例，包括123例死亡(0.7%)，其中15例 840(%)为输入性病例，主要来自非洲和东南亚。到2015年，中国(2 855/2 858)几乎所有县都实现了消灭目标，本地传播病例从2011年的1 469例下降到2015年的43例，主要发生在与缅甸接壤的微小按蚊和按蚊的地区。大劣按蚊为优势媒介种。2011-2015年间，在消除疟疾方面总共花费了1.346亿美元，其中全球抗击艾滋病、结核病和疟疾基金提供了5.572亿美元(43%)，中国中央政府提供了7.773亿美元(57%)。平均每人每年的投资(2.7亿美元 )为5.74亿 (标准差：0.03)。中国就地传播疟疾负担减轻。关键的挑战是解决剩余的本地传播问题，以及减少从非洲和东南亚输入的病例。在2016-2020年期间，需要继续努力并进行适当水平的投资，才能实现消除。
To ascertain the trends and burden of malaria in China and the costs of interventions for 2011–2015. We analysed the spatiotemporal and demographic features of locally transmitted and imported malaria cases using disaggregated surveillance data on malaria from 2011 to 2015, covering the range of dominant malaria vectors in China. The total and mean costs for malaria elimination were calculated by funding sources, interventions and population at risk. A total of 17 745 malaria cases, including 123 deaths (0.7%), were reported in mainland China, with 15 840 (89%) being imported cases, mainly from Africa and south-east Asia. Almost all counties of China (2855/2858) had achieved their elimination goals by 2015, and locally transmitted cases dropped from 1469 cases in 2011 to 43 cases in 2015, mainly occurring in the regions bordering Myanmar where Anopheles minimus and An. dirus are the dominant vector species. A total of United States dollars (US$) 134.6 million was spent in efforts to eliminate malaria during 2011–2015, with US$ 57.2 million (43%) from the Global Fund to Fight AIDS, Tuberculosis and Malaria and US$ 77.3 million (57%) from the Chinese central government. The mean annual investment (US$ 27 million) per person at risk (574 million) was US$ 0.05 (standard deviation: 0.03). The locally transmitted malaria burden in China has decreased. The key challenge is to address the remaining local transmission, as well as to reduce imported cases from Africa and south-east Asia. Continued efforts and appropriate levels of investment are needed in the 2016–2020 period to achieve elimination.