The naturally derived insecticide spinosad is highly toxic to Aedes and Anopheles mosquito larvae
The naturally derived insecticide spinosad is highly toxic to Aedes and Anopheles mosquito larvae
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DOI：
10.1111/j.0269-283x.2004.0480.x
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发表时间：
2004-03-01
影响因子：
1.9
通讯作者：
Williams, T
中科院分区：
文献类型：
--
作者：
Bond, JG;Marina, CF;Williams, T
多杀菌素是一种天然生物杀虫剂，具有良好的环境毒性，因此我们研究了其对蚊子幼虫（双翅目：蚊科）的效力。通过多杀菌素（Tracer（R））悬浮剂对埃及伊蚊（Aedesaegypti（L.）根据logit回归，估计第三和第四龄为0.025 p. p.m.。三龄和四龄白纹按蚊的浓度-死亡率反应不符合logit模型。经二次线性回归分析，多杀菌素对白纹伊蚊的LC_（50）为0.024 p. p.m.。在墨西哥南部的一项田间试验表明，与标准的1%特美磷颗粒剂（100 g/m3水）相比，多杀菌素1 p. p.m.埃及伊蚊在装有水的塑料容器中繁殖8周;在晚上10点，多杀菌素阻止繁殖> 22周。在另一个田间试验中，多杀菌素在下午5点和temephos都完全消除了Ae的繁殖。埃及13周与此相反，细菌杀虫剂苏云金芽孢杆菌变种。Israelensis（Bti，Vectobac（R）AS）表现不佳，仅完全抑制Ae 2周。埃及养殖多杀菌素在两次试验中也有效地防止了库蚊和摇蚊的繁殖，其程度与替美磷相似。我们的结论是，多杀菌素值得评价作为替代有机磷酸盐或BTI处理生活水箱在中美洲。我们还预测，多杀菌素很可能是一种有效的杀幼虫剂，用于治疗蚊子滋生地。
Spinosad is a naturally derived biorational insecticide with an environmentally favourable toxicity profile, so we investigated its potency against mosquito larvae (Diptera: Culicidae). By laboratory bioassays of a suspension concentrate formulation of spinosad (Tracer(R)), the 24 h lethal concentration (LC50) against Aedes aegypti (L.) third and fourth instars was estimated at 0.025 p.p.m. following logit regression. The concentration-mortality response of third- and fourth-instar Anopheles albimanus Weidemann did not conform to a logit model. The LC50 value of spinosad in Anopheles albimanus was 0.024 p.p.m. by quadratic linear regression. A field trial in southern Mexico demonstrated that spinosad 1 p.p.m. compared with the standard temephos (Abate(R)) 1% granules 100 g/m(3) water prevented Ae. aegypti breeding in plastic containers of water for 8 weeks; at 10 p.p.m. spinosad prevented breeding for > 22 weeks. In another field trial, spinosad at 5 p.p.m. and temephos both completely eliminated reproduction of Ae. aegypti for 13 weeks. In contrast, the bacterial insecticide Bacillus thuringiensis var. israelensis (Bti, Vectobac(R) AS) performed poorly with just 2 weeks of complete inhibition of Ae. aegypti breeding. Spinosad also effectively prevented breeding of Culex mosquitoes and chironomids in both trials to a degree similar to that of temephos. We conclude that spinosad merits evaluation as a replacement for organophosphate or Bti treatment of domestic water tanks in Mesoamerica. We also predict that spinosad is likely to be an effective larvicide for treatment of mosquito breeding sites.