Pathogen virulence factors as molecular probes of basic plant cellular functions.
Pathogen virulence factors as molecular probes of basic plant cellular functions.
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DOI：
10.1016/j.pbi.2007.08.003
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发表时间：
2007-12
影响因子：
9.5
通讯作者：
Elena Bray Speth;Y. Lee;S. He
中科院分区：
文献类型：
--
作者：
Elena Bray Speth;Y. Lee;S. He
为了成功地定植植物，病原体已经进化出无数的毒力因子，使它们能够操纵宿主细胞途径，以便进入，繁殖和移动，并最终退出宿主进入新的感染周期。在过去的几年中，在表征病毒和细菌毒力因子的宿主靶点方面取得了实质性进展，为基因沉默、囊泡运输、激素信号传导和先天免疫等基本植物细胞过程提供了独特的见解。鉴定其他病原体毒力因子的宿主靶点有望继续阐明植物的基本细胞机制，从而增强我们对植物信号传导、代谢和细胞生物学的理解。
To successfully colonize plants, pathogens have evolved a myriad of virulence factors that allow them to manipulate host cellular pathways in order to gain entry into, multiply and move within, and eventually exit the host for a new infection cycle. In the past few years, substantial progress has been made in characterizing the host targets of viral and bacterial virulence factors, providing unique insights into basic plant cellular processes such as gene silencing, vesicle trafficking, hormone signaling, and innate immunity. Identification of the host targets of additional pathogen virulence factors promises to continue shedding light on fundamental cellular mechanisms in plants, thus enhancing our understanding of plant signaling, metabolism, and cell biology.