How modelling can help steer the course set by the World Health Organization 2021-2030 roadmap on neglected tropical diseases.

How modelling can help steer the course set by the World Health Organization 2021-2030 roadmap on neglected tropical diseases.
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DOI:
10.12688/gatesopenres.13327.2
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发表时间:
2021
影响因子:
--
通讯作者:
Hollingsworth TD
Hollingsworth TD
中科院分区:
其他
文献类型:
--
作者:
Clark J;Stolk WA;Basáñez MG;Coffeng LE;Cucunubá ZM;Dixon MA;Dyson L;Hampson K;Marks M;Medley GF;Pollington TM;Prada JM;Rock KS;Salje H;Toor J;Hollingsworth TD

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世界卫生组织最近发布了其2021-2030年路线图,即结束被忽视的热带病造成的痛苦,以实现可持续发展目标。建模和定量分析在形成这些最新目标方面发挥了重要作用。在这一系列中,我们讨论了13种目标疾病的公共卫生建模的见解,由此产生的建议和确定的挑战:恰加斯病,登革热,冈比亚人非洲锥虫病(gHAT),淋巴丝虫病(LF),盘尾丝虫病,狂犬病,疥疮,血吸虫病,土壤传播的蠕虫病(STH),猪带绦虫病/囊虫病,沙眼,内脏利什曼病(VL)和雅司病。这篇文章反映了在整个集合中确定的三个交叉主题,关于建模可以对时间表,方案设计,药物开发和临床试验做出的贡献。
The World Health Organization recently launched its 2021-2030 roadmap, Ending the Neglect to Attain the Sustainable Development Goals , an updated call to arms to end the suffering caused by neglected tropical diseases. Modelling and quantitative analyses played a significant role in forming these latest goals. In this collection, we discuss the insights, the resulting recommendations and identified challenges of public health modelling for 13 of the target diseases: Chagas disease, dengue, gambiense human African trypanosomiasis (gHAT), lymphatic filariasis (LF), onchocerciasis, rabies, scabies, schistosomiasis, soil-transmitted helminthiases (STH), Taenia solium taeniasis/ cysticercosis, trachoma, visceral leishmaniasis (VL) and yaws. This piece reflects the three cross-cutting themes identified across the collection, regarding the contribution that modelling can make to timelines, programme design, drug development and clinical trials.