Delayed ossification of the proximal capital femoral epiphysis in Legg-Calve-Perthes' disease
Delayed ossification of the proximal capital femoral epiphysis in Legg-Calve-Perthes' disease
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DOI：
10.1302/0301-620x.85b1.13426
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发表时间：
2003-01-01
影响因子：
--
通讯作者：
Takamine, Y
中科院分区：
文献类型：
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作者：
Kitoh, H;Kitakoji, T;Takamine, Y
我们研究了125名儿童（105名男孩，20名女孩）单侧Legg-Calve-Perthes病的X线片，以检查对侧（未受影响）髋关节股骨头的骨骺发育。在首次骨盆前后位X线片上测量了健侧髋关节的骨骺高度（EH）和宽度（EW），其中109例（87.2%）的EH低于日本正常儿童的平均值，23例（18.4%）的EH明显小于-2sbs。相比之下，大多数患者（95.2%）的EW位于正常值的+/- 2 SDS范围内，但6例EW明显较小。在患者中观察到EH：EW比值呈强正线性相关（R = 0.87）。在我们的研究中，EW的EH比预期的要小，这表明Legg-Calve-Perthes病的股骨头骨骺变平，我们的研究结果支持了这样一个假设，即近端股骨头骨骺的软骨内骨化延迟可能与Perthes病的发病有关。
We studied radiographs of 125 children (105 boys, 20 girls) with unilateral Legg-Calve-Perthes' disease to examine the epiphyseal development of the femoral head in the contralateral (unaffected) hip. The epiphyseal height (EH) and width (EW) of the unaffected hip were measured on the initial anteroposterior pelvic radiograph.In 109 of the patients (87.2%) the EH was below the mean for normal Japanese children and a significantly small EH (below -2 sbs) was observed in 23 patients (18.4%). By contrast, the EW of most patients (95.2%) lay within +/- 2 SDS of normal values except for six with a significantly small EW. A strong positive linear correlation (R = 0.87) was observed in the EH:EW ratio in the patients. A smaller EH than expected for EW in our series indicated epiphyseal flattening of the femoral head in Legg-Calve-Perthes' disease.Our findings support the hypothesis that a delay in endochondral ossification in the proximal capital femoral epiphysis may be associated with the onset of Perthes' disease.