Reduced N-cadherin expression is associated with metastatic potential and poor surgical outcomes of hepatocellular carcinoma

Reduced N-cadherin expression is associated with metastatic potential and poor surgical outcomes of hepatocellular carcinoma
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N-钙粘蛋白表达减少与肝细胞癌的转移潜力和不良手术结果相关

DOI:
10.1111/j.1440-1746.2011.06847.x
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发表时间:
2012-01-01
影响因子:
4.1
通讯作者:
Huang, Zhi-yong
Huang, Zhi-yong
中科院分区:
医学3区
文献类型:
--
作者:
Zhan, Da-qian;Wei, Shuang;Huang, Zhi-yong

文献摘要

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背景与目的:N-钙粘蛋白(N-cadherin,N-cad)是经典的钙粘蛋白之一,在某些类型的肿瘤转移中起重要作用。本研究旨在探讨N-cad在肝细胞癌(HCC)中的表达状况及其与HCC转移潜能和手术预后的关系。
Background and Aim: N-cadherin (N-cad), one of the classic cadherins, has been reported to be involved in tumor metastasis in some types of tumors. This study aims to investigate the expression status of N-cad in hepatocellular carcinoma (HCC) and the correlation between N-cad expression and metastatic potential, as well as the surgical outcomes of HCC.