Monthly mortality from Alzheimer’s disease and other dementia in Japan
Monthly mortality from Alzheimer’s disease and other dementia in Japan
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日本阿尔茨海默病和其他痴呆症的每月死亡率
DOI：
10.1002/alz.057632
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Naito Tomoyoshi
中科院分区：
文献类型：
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作者：
Kanamori Masao;Suzuki Mizue;Kanamori Takuya;Naito Tomoyoshi
背景本研究的目的是研究日本痴呆症死亡率的季节性变化，并追踪COVID-19造成的超额死亡。截至2021年Marciano，在英格兰为老年痴呆症患者提供护理服务的家庭中，COVID-19超额死亡率较高。我们研究了温度与死亡率的关系。死亡率最低的最适温度是最高温度的第84百分位。我们比较了2019年和2020年之间每月死亡率的变化，并考虑到迄今为止温度的影响，研究了与COVID-19相关的痴呆症是否存在间接影响。方法从2019年至2020年日本人口动态统计中提取的痴呆症（G30、阿尔茨海默病、F01 - 03、血管性痴呆和其他）的月死亡人数，获得65岁及以上年龄组的痴呆症死亡率。我们使用作者已经公布的自2001年以来NCD的月温度和月死亡率的最佳曲线估计了超额死亡率。结果2019 - 2020年痴呆症的季节性变化被评估为与月温度和死亡率的最佳曲线估计一致。然而，基于2019年按性别-年龄-类别划分的2020年死亡率在6月，8月和10月急剧上升，年龄为65 - 69岁，10月（10.2 - 43.8%）为70 - 74岁。5 - 8月，福尔斯、交通事故减少，同期老年人不包括意外事故的总死亡率下降，10月以后70岁及以上老年人死亡率上升8%。讨论：无法检测2020年COVID-19对痴呆症的影响。自2021年1月以来，日本的老年医疗设施集群数量大幅增加，长期不进行体力活动是免疫功能下降的一个因素，可能会增加痴呆症的死亡率。有限制的基础上的重要statistics.ConclusionExcess死亡率从痴呆症是无法检测到的，在2020年，但在秋季后的某些年龄组中观察到死亡率增加。
BackgroundThe aim of this study is to research seasonal changes in dementia mortality in Japan and to pursue the excess death on COVID‐19. COVID‐19 excess mortality were higher in homes providing nursing services to older people with dementia in England by Marciano, 2021. We have been researched the temperature‐mortality associations. The optimum temperature with the lowest mortality rate is the 84th percentile of the maximum temperature. We compared the changes in monthly mortality between 2019 and 2020, and examined whether there is an indirect effect on dementia associated with COVID‐19, considering the effects of temperature so far. For comparison, the total deaths of the elderly and accidental deaths such as falls were used.MethodFrom the monthly death from dementia (G30, Alzheimer disease, F01‐03, Vascular Dementia and Other) extracted from the vital statistics in Japan from 2019 to 2020, the dementia mortality rate by sex‐age group aged 65 and over was obtained. We estimated excess mortality using estimates from the optimal curves of monthly temperatures and monthly mortality rates for NCD since 2001, which the author has already announced.ResultSeasonal changes in dementia in 2019‐2020 were assessed to be consistent with estimates from optimal curves for monthly temperature and mortality. However, the 2020 mortality by gender‐age‐class based on 2019 increased sharply in June, August and October for ages 65‐69 and in October (10.2‐43.8 percent) for ages 70‐74. From May to August, falls and traffic accidents decreased, the total mortality of the elderly excluding accidents decreased during the same period, and the mortality of aged 70 and over increased by 8 percent after October. Discussion: The effect of COVID‐19 on dementia in 2020 could not be detected. Since the number of clusters of geriatric medical facilities in Japan has increased significantly since January 2021, long‐term inactivity of physical activity as a factor of immune function decline may increase the mortality from dementia. There are limits based on vital statistics.ConclusionExcess mortality from Dementia was undetectable in 2020, but an increased mortality was observed in certain age groups after the autumn.