Folding and association of a homotetrameric protein complex in an all-atom Go model.
Folding and association of a homotetrameric protein complex in an all-atom Go model.
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DOI：
10.1103/physreve.87.014701
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发表时间：
2013-01
期刊：
影响因子：
--
通讯作者：
Hansmann UH
中科院分区：
文献类型：
--
作者：
Berhanu WM;Jiang P;Hansmann UH
The 84-residue homotetrameric BBAT1 is one of the smallest stable protein complexes and therefore a good test system to study the self-assembly of multimeric proteins. We have researched for this protein the interplay between folding of monomers and their assembly into tetramers. Replica exchange molecular dynamics simulations relying on a Go-model are compared with earlier simulations that use the physics-based coarse-grained UNRES model.
