Quantitative studies on the Langerhans cell population of guinea pig epidermis.

Quantitative studies on the Langerhans cell population of guinea pig epidermis.
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豚鼠表皮朗格汉斯细胞群的定量研究。

DOI:
10.1038/jid.1967.82
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发表时间:
1967
期刊:
The Journal of investigative dermatology
影响因子:
--
通讯作者:
R. Winkelmann
R. Winkelmann
中科院分区:
--
文献类型:
--
作者:
K. Wolff;R. Winkelmann

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ATP酶阳性细胞位于表皮的基底层上,它们的突起延伸到周围的上皮,偶尔到达颗粒层以及真皮和表皮之间的交界处。这些细胞在毛皮脂管中较多,但在基底细胞层中很少见到。ATP酶阳性的树突状细胞不含黑色素,用多巴技术处理的连续切片显示细胞为多巴阴性。ATFase酶反应在所有观察到的树突细胞中同样强烈,并且在它们的表皮内分布和尺寸Fm中没有观察到区域差异。1.白化病豚鼠耳表皮朗格汉斯细胞。(ATP酶;>< 750。)
ATPase-positive cells were located in suprabasal levels of the epidermis; their processes extended far into the surrounding epithelium, occasionally reaching the granular layer as well as the junction between the dermis and epidermis. They were distributed in a rather dense pattern (Fig. 2A), but anastomoses be-tween their branches were not observed.These cells were numerous in the pilosebaeeous canals (Fig. 3), but rarely were seen in the basal cell layer (Fig. 2A). The ATPase-positive dendnitie cells did not contain melanin, and serial sections treated with the dopa technic revealed that the cells were dopa-negative. The ATFase enzymatic reaction was equally intense in all of the dendritie cells observed, and no regional differences were seen in their intra-epidermal distribution and size Fm. 1. Langerhans cells in epidermis of albino guinea pig ear.(ATPase;>< 750.)