Central organization of a high-dimensional odor space
Central organization of a high-dimensional odor space
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DOI：
10.1016/j.conb.2022.102528
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发表时间：
2022-03
影响因子：
5.7
通讯作者：
Keita Endo;H. Kazama
中科院分区：
文献类型：
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作者：
Keita Endo;H. Kazama
动物将气味的组合和混合物识别为一个单一的物体。这种能力对于将已知的气味概括为新遇到的气味至关重要，尽管变化。然而，它仍然在很大程度上是未知的，如何众多的气味表示和组织在更高的大脑区域，以支持气味物体识别。在这里，我们讨论了最新的进展，揭示了人口的气味反应在啮齿动物梨状皮质和theDrosophilamushroom身体，并强调新兴的原则上的组织，机制，刻板印象，和经验依赖的中央气味表示。
Animals recognize groups and mixtures of odors as a unitary object. This ability is crucial to generalize known odors to newly encountered ones despite variations. However, it remains largely unknown how multitudes of odors are represented and organized in the higher brain regions to support odor object recognition. Here we discuss recent advances uncovering the population odor responses in the rodent piriform cortex and theDrosophilamushroom body, and highlight the emerging principles on the organization, mechanism, stereotypy, and experience-dependence of central odor representations.