A severe H7N9 pneumonia with syndrome of inappropriate antidiuresis and vitamin D deficiency.
A severe H7N9 pneumonia with syndrome of inappropriate antidiuresis and vitamin D deficiency.
复制标题
严重 H7N9 肺炎伴抗利尿不当和维生素 D 缺乏综合征
DOI：
10.1016/j.rmcr.2014.03.001
复制
发表时间：
2014
影响因子：
1.1
通讯作者：
Lin, Caijing
中科院分区：
文献类型：
--
作者：
Lin, Leng;Yao, Jin;Chen, Gang;Lin, Caijing
一些H7N9患者出现低钠血症。但SIAD是否可能是H7N9肺炎低钠血症的病因尚不清楚。入组了一例H7N9患者。评价临床体征。测定有效渗透压、尿渗透压、尿钠、甲状腺功能、肾上腺功能、25（OH）维生素D和细胞免疫功能。(1)结果显示，患者血清渗透压低，尿渗透压不适当升高，尿钠浓度升高，血清尿酸浓度低，血清肌酐浓度相对正常，酸碱和钾平衡正常，肾上腺和甲状腺功能正常。(2)我们的病人表现为维生素D缺乏和细胞免疫功能下降。一些H7N9肺炎可能导致SIAD。H7N9肺炎中SIAD的早期检测和适当治疗可能很重要。我们的病人表现为维生素D缺乏和细胞免疫功能下降。
Some H7N9 patients presented with hyponatremia. But whether SIAD could be the etiology of hyponatremia in H7N9 pneumonia is still not known. A H7N9 patient was enrolled. Clinical sign were evaluated. Effective osmolality, urinary osmolality, urinary sodium, thyroid function, adrenal function, 25(OH) Vitamin D and cellular immune function were measured. (1) The results showed low serum osmolality, inappropriately elevated urine osmolality, elevated urine sodium concentration, low serum uric acid concentration, relatively normal serum creatinine concentration, normal acid-base and potassium balance, normal adrenal and thyroid function in our patient. (2) Our patient showed vitamin D deficiency and decline of cellular immune function. Some H7N9 pneumonia could cause SIAD. Early detection and appropriate treatment of SIAD in H7N9 pneumonia might be important. Our patient showed vitamin D deficiency and decline of cellular immune function.