Scan findings of various myocardial SPECT agents in a case of amyloid polyneuropathy with suspected myocardial involvement
Scan findings of various myocardial SPECT agents in a case of amyloid polyneuropathy with suspected myocardial involvement
复制标题
疑似心肌受累的淀粉样多发性神经病病例中各种心肌 SPECT 药物的扫描结果
作者：
A. Arbab;K. Koizumi;K. Toyama;T. Arai;Tatsuya Yoshitomi;T. Araki
一名31岁男性患有家族性淀粉样多发性神经病，接受了Tc-99 m（V）-DMSA研究以评估心肌受累。患者还接受了Tl-201、I-123-BMIPP和I-123-MIBG心肌SPECT研究，以分别评价心脏的血液灌注、脂肪酸代谢和交感神经功能。Tc-99 m（V）-DMSA SPECT显示心肌摄取，表明心肌淀粉样变性。Tl-201和I-123-BMIPP研究均显示正常摄取，表明血液灌注和脂肪酸代谢正常，但I-123-MIBG SPECT显示心脏无摄取，表明交感神经功能严重受损。
A 31-year-old male having familial amyloid polyneuropathy underwent a Tc-99m(V)-DMSA study to evaluate the myocardial involvement. The patient also underwent Tl-201, I-123-BMIPP and I-123-MIBG myocardial SPECT studies to evaluate blood perfusion, fatty acid metabolism and sympathetic function of the heart, respectively. Tc-99m(V)-DMSA SPECT showed uptake to the myocardium indicating myocardial involvement of amyloidosis. Both Tl-201 and I-123-BMIPP studies showed normal uptake indicating normal blood perfusion and fatty acid metabolism but I-123-MIBG SPECT showed no uptake to the heart, indicating severe impairment of sympathetic function.