Assessment of the coronary calcification by optical coherence tomography
Assessment of the coronary calcification by optical coherence tomography
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DOI：
10.4244/eijv6i6a130
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发表时间：
2011-01-01
期刊：
影响因子：
6.2
通讯作者：
Yoshida, Kiyoshi
中科院分区：
文献类型：
--
作者：
Kume, Teruyoshi;Okura, Hiroyuki;Yoshida, Kiyoshi
目的：光学相干断层扫描（OCT）可以无伪影地描绘钙化斑块。本研究的目的是评估能力的OCT量化钙化斑块在离体human coronary arteries.Methods和results：91冠状动脉段从33个连续的人尸体进行了检查。通过血管内超声（IVUS），选择了32个浅表钙化斑块，定义为声影的前缘出现在最浅的50%斑块加中膜厚度内，并与相应的OCT和组织学检查进行比较。通过面积测量法测量钙化面积。与组织学检查相比，IVUS明显低估了钙化面积（y=0.39x+0.14，r=0.78，p
Aims: Optical coherence tomography (OCT) can delineate calcified plaque without artefacts. The aim of this study was to evaluate the ability of OCT to quantify calcified plaque in ex vivo human coronary arteries.Methods and results: Ninety-one coronary segments from 33 consecutive human cadavers were examined. By intravascular ultrasound (IVUS), 32 superficial calcified plaques, defined as the leading edge of the acoustic shadowing appears within the most shallow 50% of the plaque plus media thickness, were selected and compared with corresponding OCT and histological examinations. The area of calcification was measured by planimetry. IVUS significantly underestimated the area of calcification compared with histological examination (y=0.39x+0.14, r=0.78, p