Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients
Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients
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DOI：
10.1016/j.jpainsymman.2007.01.016
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发表时间：
2007-12-01
影响因子：
4.7
通讯作者：
Buckner, Jan C.
中科院分区：
文献类型：
--
作者：
Locke, Dona E. C.;Decker, Paul A.;Buckner, Jan C.
对患者生活质量（QOL）的评估需要在多项评估提供的细节与单项评估减轻的负担之间取得平衡。在这个项目中，我们研究了单项目线性模拟量表评估（LASAs）对新诊断的高级别胶质瘤患者的心理测量特性。测量包括生活质量LASAs（总体、身体、情绪、精神、智力）、症状困扰量表（SDS）、情绪状态谱（POMS；总体、困惑、疲劳）和癌症治疗-脑功能评估（FACT-Br；总体、大脑、身体、情绪）。评估LASA措施与SDS、POMS和FACT-Br结构域以及与东部肿瘤合作组绩效评分（PS）和迷你精神状态检查（MMSE）的关联。重复测量方差分析模型比较了LASAs与SDS、POMS和FACT-Br随时间的变化。225名患者在三个时间点完成了评估。为了进行比较，所有的分数都被转换成0-100的范围，分数越高表明生活质量越好。LASA平均评分范围为60 - 78；SDS、POMS和FACT-Br的范围从62到81。FACT-Br物理（P < 0.001）和POMS疲劳子量表（P = 0.005）随着时间的推移而下降，LASA物理（P = 0.08）也是如此。LASA量表与相应的SDS、POMS和FACT-Br量表呈强相关（0.44 < rho < 0）。65年;P < 0.001)。LASA与PS呈负相关，与MMSE呈正相关，与其他生活质量和社会心理测量的关联程度相似。数据表明单项LASA量表对评估癌症患者的生活质量是有效的，当需要更短的工具时，它是一个合适的选择。
Assessment of patient quality of life (QOL) requires balancing the details provided by multi-item assessments with the reduced burden of single-item assessments. In this project, we investigated the psychometric properties of single-item Linear Analog Scale Assessments (LASAs) for patients with newly diagnosed high-grade gliomas. Measures included QOL LASAs (overall, physical, emotional, spiritual, intellectual), Symptom Distress Scale (SDS), Profile of Mood States (POMS; overall, confusion, fatigue), and Functional Assessment of Cancer Therapy-Brain (FACT-Br; overall, brain, physical, emotional). Associations of LASA measures with SDS, POMS, and FACT-Br domains and with Eastern Cooperative Oncology Croup performance score (PS) and Mini-Mental State Examination (MMSE) were assessed. Repeated measures ANOVA models compared the change over time of LASAs and SDS, POMS, and FACT-Br. Two hundred five patients completed the assessments across three time points. To allow comparison across measures, all scores were converted to a scale of 0-100, with higher scores indicating better QOL. LASA mean scores ranged from 60 to 78; SDS, POMS, and FACT-Br ranged from 62 to 81. FACT-Br physical (P < 0.001) and POMS fatigue subscale (P = 0.005) decreased over time, as did LASA physical (P = 0.08). LASA scales were strongly associated with corresponding scales on SDS, POMS, and FACT-Br (0.44 < rho < 0. 65; P < 0.001). LASA was negatively associated with PS and positively with MMSE, with associations similar in magnitude to the other QOL and psychosocial measures. The data suggest that the single-item LASA scales are valid for assessing QOL of cancer patients and are an appropriate alternative when a shorter instrument is warranted.