Selective breeding for juvenile survival in Chinese tongue sole (Cynoglossus semilaevis): Heritability and selection response
Selective breeding for juvenile survival in Chinese tongue sole (Cynoglossus semilaevis): Heritability and selection response
复制标题
DOI：
10.1016/j.aquaculture.2020.735901
复制
发表时间：
2021-01
期刊：
影响因子：
4.5
通讯作者：
Yangzhen Li;Yuanri Hu;Yingming Yang;Weiwei Zheng;Changshan Chen;Zhongming Li
中科院分区：
文献类型：
--
作者：
Yangzhen Li;Yuanri Hu;Yingming Yang;Weiwei Zheng;Changshan Chen;Zhongming Li
中国舌鳎（Cynoglossus semilaevis）是一种经济上重要的海洋比目鱼，目前在中国受到各种细菌病原体的严重威胁，特别是在幼鱼阶段。众所周知，提高养殖鱼类的自然抗病能力是非常重要的。因此，本研究的目的是利用幼崽自然生存数据（涉及4年班，3代，221个全同胞家庭，195,589个个体）验证自然抗病遗传变异的存在性，并检测选择反应。生存被定义为两个横截面模型（即横截面线性水坝模型（CLM）和横截面阈值（logit）水坝模型（CTM））拟合的二元特征（死/活）。用每代数据集和完整数据集估计生存的遗传力。无论使用何种模型，各代之间的遗传力估计值都存在差异，即CLM和CTM的遗传力估计值分别为0.01-0.17和0.03-0.25。在完整数据集的观测（CLM）和底层（CTM）尺度上，遗传度分别为0.09±0.04和0.13±0.06。两种模型的选择精度几乎相同，且非常高（> 0.99），CLM的选择精度（0.993）略高于CTM（0.991）。经交叉验证，CLM的预测准确率比CTM高21%，CLM和CTM的预测准确率分别为0.885和0.730。平均每代预测遗传增益为14.89%，平均每代实现遗传增益为8.10%。这些结果证实了遗传变异对幼鱼自然生存的影响，并强调了通过选择育种提高舌鳎自然生存的巨大潜力。
Chinese tongue sole (Cynoglossus semilaevis) is an economically important marine flatfish which is now severely threatened by various bacterial pathogens (especially at juvenile stage) in China. As we all known, it is of great importance to increase the natural disease resistance of farmed fish. So, the aim of this study was to verify the exitance of genetic variance of natural disease resistance and to detect the selection response by using juvenile natural survival data (involving four year-classes and three generations with 221 full-sib families, 195,589 individuals). Survival was defined as binary trait (dead/alive) fitted in two cross-sectional models (i.e. cross-sectional linear sire-dam model (CLM) and cross-sectional threshold (logit) sire-dam model (CTM)). Heritabilities of survival were estimated with each generation dataset and with complete dataset. Heritability estimates varied among generations regardless of model used, i.e., 0.01–0.17 and 0.03–0.25 for CLM and CTM respectively. On the observed (CLM) and underlying (CTM) scale with complete dataset, the heritabilities were 0.09 ± 0.04 and 0.13 ± 0.06 respectively. Both models performed nearly identical and very high selection accuracy (> 0.99), the accuracy of selection obtained from CLM (0.993) was slightly higher than CTM (0.991). By cross-validation, the prediction accuracy of CLM is 21% higher than CTM, which was 0.885 and 0.730 for CLM and CTM respectively. The average of predicted genetic gain for each generation was 14.89%, and the average of realized genetic gain was 8.10% per generation for juvenile survival. These results confirmed the existence of genetic variation for juvenile natural survival and highlighted the enormous potential for improving natural survival by selective breeding in tongue sole.