Reconsidering plant memory: Intersections between stress recovery, RNA turnover, and epigenetics.
Reconsidering plant memory: Intersections between stress recovery, RNA turnover, and epigenetics.
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DOI：
10.1126/sciadv.1501340
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发表时间：
2016-02
期刊：
影响因子：
13.6
通讯作者：
Pogson BJ
中科院分区：
文献类型：
--
作者：
Crisp PA;Ganguly D;Eichten SR;Borevitz JO;Pogson BJ
植物学会忘记压力了吗？这篇综述提出了对健忘的益处，并发现了RNA转换的关键作用。植物生长在动态环境中，它们可能暴露于多种压力因素，所有这些因素都会影响它们的发育，产量，并最终影响生殖成功。植物擅长快速适应压力条件，并且能够通过保留压力记忆来进一步加强它们的防御，以便在环境扰动再次发生时能够做出更强或更快速的反应。事实上，一种经常被唤起的关于环境记忆的机制是表观遗传学。然而，这种记忆的例子相对较少；考虑到自然界中过多的压力，对它们的持续时间也没有一个明确的认识。我们建议，这一领域将受益于研究过程和机制，使从压力中恢复。对压力恢复的理解可以为环境记忆何时、如何以及为什么被创造和调节提供新的见解。应激记忆可能不适应，阻碍恢复，影响发育和潜在产量。在某些情况下，植物学会遗忘可能是有益的。因此，恢复过程需要在重置和记忆形成之间进行平衡。在恢复过程中，RNA代谢、转录后基因沉默和RNA定向DNA甲基化可能在重置表观基因组和转录组以及改变记忆中发挥关键作用。随着基因组学、表型组学和高通量测序方法的进步，这一新兴研究领域的探索变得越来越容易处理，这将使高分辨率应激恢复时间序列实验和大型自然种群采样的分析成为可能。
Have plants learned to forget stress? This review proposes benefits to forgetfulness and finds key roles for RNA turnover. Plants grow in dynamic environments where they can be exposed to a multitude of stressful factors, all of which affect their development, yield, and, ultimately, reproductive success. Plants are adept at rapidly acclimating to stressful conditions and are able to further fortify their defenses by retaining memories of stress to enable stronger or more rapid responses should an environmental perturbation recur. Indeed, one mechanism that is often evoked regarding environmental memories is epigenetics. Yet, there are relatively few examples of such memories; neither is there a clear understanding of their duration, considering the plethora of stresses in nature. We propose that this field would benefit from investigations into the processes and mechanisms enabling recovery from stress. An understanding of stress recovery could provide fresh insights into when, how, and why environmental memories are created and regulated. Stress memories may be maladaptive, hindering recovery and affecting development and potential yield. In some circumstances, it may be advantageous for plants to learn to forget. Accordingly, the recovery process entails a balancing act between resetting and memory formation. During recovery, RNA metabolism, posttranscriptional gene silencing, and RNA-directed DNA methylation have the potential to play key roles in resetting the epigenome and transcriptome and in altering memory. Exploration of this emerging area of research is becoming ever more tractable with advances in genomics, phenomics, and high-throughput sequencing methodology that will enable unprecedented profiling of high-resolution stress recovery time series experiments and sampling of large natural populations.