Joint symbolic dynamic analysis of beat-to-beat interactions of heart rate and systolic blood pressure in normal pregnancy
Joint symbolic dynamic analysis of beat-to-beat interactions of heart rate and systolic blood pressure in normal pregnancy
复制标题
DOI：
10.1007/bf02348131
复制
发表时间：
2002-03-01
影响因子：
3.2
通讯作者：
Voss, A
中科院分区：
文献类型：
--
作者：
Baumert, M;Walther, T;Voss, A
妊娠引起自主神经控制的重要变化。心率（HR）变异性和收缩压（SP）变异性的测量对这些变化敏感。HR和SP之间的相互作用是复杂的和强非线性的。因此，它们不能完全用线性分析技术描述。联合符号动力学研究是一种新的短期非线性分析方法，用于研究HR和SP之间的相互作用。分析了25名孕妇和14名非孕妇的连续、无创30分钟血压记录（Portapres）。提取心跳间心率和SP的时间序列。使用联合符号动力学的概念，HR和SP的变化被转换成一个双变量符号向量。随后，将该符号向量转换为单词系列（由三个连续符号组成的单词），计算每种单词类型的出现概率，并在两组之间进行比较。孕妇和非孕妇在五种词类型上存在显著差异：w（0，4）（0.021 +/- 0.011对0.008 +/- 0.006; p = 0.022），w（4，6）（0.020 +/- 0.010对比0.007 +/- 0.003，p = 0.001），w（3，2）（0.004 +/- 0.003对比0.007 +/- 0.003，p = 0.038），w（6，5）（0.009 +/- 0.007对比0.023 +/- 0.008; p
Pregnancy induces important changes in the autonomic control. Measures of heart rate (HR) variability and systolic blood pressure (SP) variability are sensitive to those changes. The interactions between HR and SP are complex and strongly non-linear. Therefore they cannot be completely described by linear analysis techniques. A study of joint symbolic dynamics is presented as a new short-term non-linear analysis method to investigate the interactions between HR and SP. Continuous, non-invasive 30 min blood pressure recordings (Portapres) of 25 pregnant and 14 non-pregnant women were analysed. Time series of beat-to-beat HR and SP were extracted. Using the concept of joint symbolic dynamics, HR and SP changes were transformed into a bivariate symbol vector. Subsequently, this symbol vector was transformed into a word series (words consisting of three successive symbols), and the probability of occurrence of each word type was calculated and compared between both groups. Significant differences were found in five word types between pregnant and non-pregnant women: w(0,4)(0.021 +/- 0.011 against 0.008 +/- 0.006; p = 0.022), w(4,6)(0.020 +/- 0.010 against 0.007 +/- 0.003, p = 0.001), w(3,2)(0.004 +/- 0.003 against 0.007 +/- 0.003, p = 0.038), w(6,5)(0.009 +/- 0.007 against 0.023 +/- 0.008; p